Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults

Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults

Objectives: To characterize the clinical correlates of subclinical Parkinsonian signs, including longitudinal cognitive and neural (via functional connectivity) outcomes, among functionally normal older adults.Methods: Participants included 737 functionally intact community-dwelling older adults who...

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Bibliographic Details
Main Authors: Jennifer Zitser, Kaitlin B. Casaletto, Adam M. Staffaroni, Claire Sexton, Sophia Weiner-Light, Amy Wolf, Jesse A. Brown, Bruce L. Miller, Joel H. Kramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
parkinsonism
UPDRS
cognition
fMRI
motor signs
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.594637/full

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