MLP-UNet: Glomerulus Segmentation

Glomerulus segmentation in kidney tissue segments is a crucial nephropathology process used to diagnose renal diseases effectively. This study proposes a novel and robust application of MLP (Multi-Layer Perceptron) based architectures for the segmentation of glomeruli in PAS (Periodic AcidSchiff) st...

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Main Authors: Franchis N. Saikia, Yuji Iwahori, Taisei Suzuki, M. K. Bhuyan, Aili Wang, Boonserm Kijsirikul
Format: Article
Language:English
Published: IEEE 2023-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10138195/
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author Franchis N. Saikia
Yuji Iwahori
Taisei Suzuki
M. K. Bhuyan
Aili Wang
Boonserm Kijsirikul
author_facet Franchis N. Saikia
Yuji Iwahori
Taisei Suzuki
M. K. Bhuyan
Aili Wang
Boonserm Kijsirikul
author_sort Franchis N. Saikia
collection DOAJ
description Glomerulus segmentation in kidney tissue segments is a crucial nephropathology process used to diagnose renal diseases effectively. This study proposes a novel and robust application of MLP (Multi-Layer Perceptron) based architectures for the segmentation of glomeruli in PAS (Periodic AcidSchiff) stained whole renal images for effective diagnosis of renal diseases. For the segmentation challenge, the proposed unique solution uses MLP-UNet (Multi-Layer Perceptron U-Net), a novel design that evades using conventional convolution and self-attention mechanisms. Additionally, the study compares various approaches, including U-Net, and for the first time, trains the TransUNet model on the kidney WSI (Whole Slide Image) dataset. Dice Score and Dice Loss were used for training these models as the metric and loss function. Results showed that MLP-based architectures provide comparable results (89.96%) to pre-trained architectures like TransUNet (90.58%) with effectively 20% lesser parameters and no pre-training, and also produce superior Dice scores across the 5-fold cross-validation training and learn more quickly than conventional U-Net architectures.
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spelling doaj.art-f742e7c046c44d1196c93712ec212fa62023-06-05T23:00:17ZengIEEEIEEE Access2169-35362023-01-0111530345304710.1109/ACCESS.2023.328083110138195MLP-UNet: Glomerulus SegmentationFranchis N. Saikia0https://orcid.org/0000-0002-9544-5971Yuji Iwahori1https://orcid.org/0000-0002-6421-8186Taisei Suzuki2M. K. Bhuyan3https://orcid.org/0000-0003-2152-5466Aili Wang4https://orcid.org/0000-0002-9118-230XBoonserm Kijsirikul5https://orcid.org/0000-0002-9046-7151Department of Electronics and Communication Engineering, Indian Institute of Technology Guwahati, Guwahati, IndiaDepartment of Computer Science, Chubu University, Kasugai, JapanDepartment of Nephrology, Nagoya City University East Medical Center, Nagoya, JapanDepartment of Electronics and Electrical Engineering, Indian Institute of Technology Guwahati, Guwahati, IndiaHigher Education Key Laboratory for Measuring and Control Technology and Instrumentations of Heilongjiang, Harbin University of Science and Technology, Harbin, ChinaDepartment of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, ThailandGlomerulus segmentation in kidney tissue segments is a crucial nephropathology process used to diagnose renal diseases effectively. This study proposes a novel and robust application of MLP (Multi-Layer Perceptron) based architectures for the segmentation of glomeruli in PAS (Periodic AcidSchiff) stained whole renal images for effective diagnosis of renal diseases. For the segmentation challenge, the proposed unique solution uses MLP-UNet (Multi-Layer Perceptron U-Net), a novel design that evades using conventional convolution and self-attention mechanisms. Additionally, the study compares various approaches, including U-Net, and for the first time, trains the TransUNet model on the kidney WSI (Whole Slide Image) dataset. Dice Score and Dice Loss were used for training these models as the metric and loss function. Results showed that MLP-based architectures provide comparable results (89.96%) to pre-trained architectures like TransUNet (90.58%) with effectively 20% lesser parameters and no pre-training, and also produce superior Dice scores across the 5-fold cross-validation training and learn more quickly than conventional U-Net architectures.https://ieeexplore.ieee.org/document/10138195/Computer visionimage segmentationsemantic segmentationdeep learningbiomedical image processingartificial intelligence
spellingShingle Franchis N. Saikia
Yuji Iwahori
Taisei Suzuki
M. K. Bhuyan
Aili Wang
Boonserm Kijsirikul
MLP-UNet: Glomerulus Segmentation
IEEE Access
Computer vision
image segmentation
semantic segmentation
deep learning
biomedical image processing
artificial intelligence
title MLP-UNet: Glomerulus Segmentation
title_full MLP-UNet: Glomerulus Segmentation
title_fullStr MLP-UNet: Glomerulus Segmentation
title_full_unstemmed MLP-UNet: Glomerulus Segmentation
title_short MLP-UNet: Glomerulus Segmentation
title_sort mlp unet glomerulus segmentation
topic Computer vision
image segmentation
semantic segmentation
deep learning
biomedical image processing
artificial intelligence
url https://ieeexplore.ieee.org/document/10138195/
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AT yujiiwahori mlpunetglomerulussegmentation
AT taiseisuzuki mlpunetglomerulussegmentation
AT mkbhuyan mlpunetglomerulussegmentation
AT ailiwang mlpunetglomerulussegmentation
AT boonsermkijsirikul mlpunetglomerulussegmentation