Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants
Pathogenesis of depression is similar to that of cancer in many aspects. Important mechanisms include effects on hypothalamo-pituitary-adrenal axis (HPA axis), functions of prostaglandins, inflammatory markers and cellular immunity. Anti-depressants must have the actions through above mentioned mech...
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2021-03-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/552 |
| _version_ | 1827370364190064640 |
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| author | Abhijeet Faye |
| author_facet | Abhijeet Faye |
| author_sort | Abhijeet Faye |
| collection | DOAJ |
| description | Pathogenesis of depression is similar to that of cancer in many aspects. Important mechanisms include effects on hypothalamo-pituitary-adrenal axis (HPA axis), functions of prostaglandins, inflammatory markers and cellular immunity. Anti-depressants must have the actions through above mentioned mechanisms when used to treat depression. Literature has mentioned the effects of various anti-depressant agents in reversing or modifying the pathogenic changes that occur in cancer too. It’s worth exploring the anti-cancer properties of anti-depressants and utilize those for the treatment of cancer whenever used for treating associated depression or other psychiatric conditions. Long term studies are needed to prove this less researched aspect of antidepressants. |
| first_indexed | 2024-03-08T10:14:11Z |
| format | Article |
| id | doaj.art-f7468cc3f1b44ec6b7df97ea423f34fc |
| institution | Directory Open Access Journal |
| issn | 2538-4635 |
| language | English |
| last_indexed | 2024-03-08T10:14:11Z |
| publishDate | 2021-03-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Biology |
| spelling | doaj.art-f7468cc3f1b44ec6b7df97ea423f34fc2024-01-29T06:19:37ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Biology2538-46352021-03-01613410.31557/apjcb.2021.6.1.3-4552Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressantsAbhijeet Faye0Consultant Psychiatrist, National Cancer Institute, Khasara No 25, Outer Hingna Ring Road, Mauza, Jamtha, Nagpur, Maharashtra, India.Pathogenesis of depression is similar to that of cancer in many aspects. Important mechanisms include effects on hypothalamo-pituitary-adrenal axis (HPA axis), functions of prostaglandins, inflammatory markers and cellular immunity. Anti-depressants must have the actions through above mentioned mechanisms when used to treat depression. Literature has mentioned the effects of various anti-depressant agents in reversing or modifying the pathogenic changes that occur in cancer too. It’s worth exploring the anti-cancer properties of anti-depressants and utilize those for the treatment of cancer whenever used for treating associated depression or other psychiatric conditions. Long term studies are needed to prove this less researched aspect of antidepressants.http://www.waocp.com/journal/index.php/apjcb/article/view/552depression, cancer, anti-depressants, anti-cancer properties. |
| spellingShingle | Abhijeet Faye Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants Asian Pacific Journal of Cancer Biology depression, cancer, anti-depressants, anti-cancer properties. |
| title | Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants |
| title_full | Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants |
| title_fullStr | Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants |
| title_full_unstemmed | Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants |
| title_short | Shared Pathogenesis in Depression and Cancer Depicting the Anti-cancer Properties of Anti-depressants |
| title_sort | shared pathogenesis in depression and cancer depicting the anti cancer properties of anti depressants |
| topic | depression, cancer, anti-depressants, anti-cancer properties. |
| url | http://www.waocp.com/journal/index.php/apjcb/article/view/552 |
| work_keys_str_mv | AT abhijeetfaye sharedpathogenesisindepressionandcancerdepictingtheanticancerpropertiesofantidepressants |