A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans

A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans

Summary: RNA interference (RNAi) is an essential regulatory mechanism in all animals. In Caenorhabditis elegans, several classes of small RNAs act to silence or license expression of mRNA targets. ERI-6/7 is required for the production of some endogenous small interfering RNAs (siRNAs) and acts as a...

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Bibliographic Details
Main Authors: Alicia K. Rogers, Carolyn M. Phillips
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Subjects:
RNAi
C. elegans
small RNA
gene regulation
feedback loop
22G-RNAs
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720312687

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