Identification of immune-related mechanisms of cetuximab induced skin toxicity in colorectal cancer patients.

Skin rash is a well-known predictive marker of the response to cetuximab (Cmab) in metastatic colorectal cancer (mCRC). However, the mechanism of skin rash development is not well understood. Following exposure to EGFR-targeted therapies, changes in IL-8 levels have been reported. The aim of this st...

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Main Authors: Jin Hyun Park, Mi Young Kim, In Sil Choi, Ji-Won Kim, Jin Won Kim, Keun-Wook Lee, Jin-Soo Kim
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2022-01-01
叢編:PLoS ONE
在線閱讀:https://doi.org/10.1371/journal.pone.0276497