Is Bartonella sp. infection relevant in hematological malignancies in HIV-negative patients? A literature review

Bartonelloses are diseases caused by Bartonella sp., transmitted to humans by blood sucking arthropod vectors. Clinical presentations include bacillary angiomatosis, cat scratch disease and atypical forms. We performed a review of cases of bartonelloses and hematological malignancies published in HI...

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Bibliographic Details
Main Authors: Elisa Nunes Secamilli, Marina Rovani Drummond, Juliana Yumi Massuda Serrano, Rafael Fantelli Stelini, Maria Leticia Cintra, Paulo Eduardo Neves Ferreira Velho
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Leukemia Research Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213048923000420
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Summary:Bartonelloses are diseases caused by Bartonella sp., transmitted to humans by blood sucking arthropod vectors. Clinical presentations include bacillary angiomatosis, cat scratch disease and atypical forms. We performed a review of cases of bartonelloses and hematological malignancies published in HIV-negative patients. Terms used were Bartonella or Bacillary Angiomatosis and Leukemia, Lymphoma, Multiple Myeloma, or Cancer. Fifteen cases met our criteria. Clinical presentations included bacillary angiomatosis, chronic fever, chronic lymphadenopathy, osteomyelitis, neuroretinitis, chronic anemia and hepatosplenic peliosis. Fourteen patients were asymptomatic after antibiotic therapy, and one died before antibiotic treatment. Clinicians should be suspicious of Bartonella sp. infections in immunocompromised patients.
ISSN:2213-0489