Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis

Aim. To describe modern approaches to the diagnosis and treatment of neuroendocrine gastric tumours associated with chronic autoimmune gastritis on the example of a clinical case.General provisions. Patient H., born in 1948, suffered from a dyspepsia syndrome, the presence of chronic exhelicobacter...

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Main Authors: S. I. Mozgovoi, M. A. Livzan, T. S. Krolevets, A. G. Shimanskaya
Format: Article
Language:Russian
Published: Gastro LLC 2020-01-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/428
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author S. I. Mozgovoi
M. A. Livzan
T. S. Krolevets
A. G. Shimanskaya
author_facet S. I. Mozgovoi
M. A. Livzan
T. S. Krolevets
A. G. Shimanskaya
author_sort S. I. Mozgovoi
collection DOAJ
description Aim. To describe modern approaches to the diagnosis and treatment of neuroendocrine gastric tumours associated with chronic autoimmune gastritis on the example of a clinical case.General provisions. Patient H., born in 1948, suffered from a dyspepsia syndrome, the presence of chronic exhelicobacter gastritis and neuroendocrine tumour of unclear histogenesis in the upper third of the stomach body. The patient also suffered from systemic lupus erythematosus with skin lesions (discoid rash, palmar and plantar capillaries) and joint lesions (migrating polyarthritis). A general clinical examination revealed mild chronic iron deficiency anemia and increased neuron-specific enolase (NSE). An EGDS examination using expert-class equipment with the NBI function of close focus identified subepithelial formations of the stomach body. The histological results showed a morphological pattern consistent with a highly differentiated neuroendocrine tumour (G1), type 1, associated with chronic autoimmune gastritis.Conclusion. The autoimmune genesis of the chronic inflammation of the gastric mucosa may serve as a background for the development of neuroendocrine tumours of the stomach, which determines the management tactics in such conditions.
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spelling doaj.art-f76a4ca3ea774779b0e2251a9ea60aec2024-03-25T16:53:08ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-01-01296495910.22416/1382-4376-2019-29-6-49-59331Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune GastritisS. I. Mozgovoi0M. A. Livzan1T. S. Krolevets2A. G. Shimanskaya3Omsk State Medical UniversityOmsk State Medical UniversityOmsk State Medical UniversityOmsk State Medical UniversityAim. To describe modern approaches to the diagnosis and treatment of neuroendocrine gastric tumours associated with chronic autoimmune gastritis on the example of a clinical case.General provisions. Patient H., born in 1948, suffered from a dyspepsia syndrome, the presence of chronic exhelicobacter gastritis and neuroendocrine tumour of unclear histogenesis in the upper third of the stomach body. The patient also suffered from systemic lupus erythematosus with skin lesions (discoid rash, palmar and plantar capillaries) and joint lesions (migrating polyarthritis). A general clinical examination revealed mild chronic iron deficiency anemia and increased neuron-specific enolase (NSE). An EGDS examination using expert-class equipment with the NBI function of close focus identified subepithelial formations of the stomach body. The histological results showed a morphological pattern consistent with a highly differentiated neuroendocrine tumour (G1), type 1, associated with chronic autoimmune gastritis.Conclusion. The autoimmune genesis of the chronic inflammation of the gastric mucosa may serve as a background for the development of neuroendocrine tumours of the stomach, which determines the management tactics in such conditions.https://www.gastro-j.ru/jour/article/view/428autoimmune gastritisneuroendocrine tumours of the stomachtacticsprognosis
spellingShingle S. I. Mozgovoi
M. A. Livzan
T. S. Krolevets
A. G. Shimanskaya
Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
autoimmune gastritis
neuroendocrine tumours of the stomach
tactics
prognosis
title Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
title_full Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
title_fullStr Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
title_full_unstemmed Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
title_short Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
title_sort neuroendocrine tumour as a diagnostic and prognostic criterion for autoimmune gastritis
topic autoimmune gastritis
neuroendocrine tumours of the stomach
tactics
prognosis
url https://www.gastro-j.ru/jour/article/view/428
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AT malivzan neuroendocrinetumourasadiagnosticandprognosticcriterionforautoimmunegastritis
AT tskrolevets neuroendocrinetumourasadiagnosticandprognosticcriterionforautoimmunegastritis
AT agshimanskaya neuroendocrinetumourasadiagnosticandprognosticcriterionforautoimmunegastritis