Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock
Introduction. Neuroendocrine neoplasms (NENs) of the gastrointestinal tract (GIT) are slow-growing and rare tumors with different clinical, histological, and biological characteristics with an increased incidence in recent years. Most of them are indolent and colonic NENs are rare among all GIT-NENs...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2023-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300042Z.pdf |
| _version_ | 1797680734050189312 |
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| author | Zogić Enes Detanac Dženana A. Brničanin Kemal Detanac Džemail S. Marovac Sead |
| author_facet | Zogić Enes Detanac Dženana A. Brničanin Kemal Detanac Džemail S. Marovac Sead |
| author_sort | Zogić Enes |
| collection | DOAJ |
| description | Introduction. Neuroendocrine neoplasms (NENs) of the gastrointestinal tract (GIT) are slow-growing and rare tumors with different clinical, histological, and biological characteristics with an increased incidence in recent years. Most of them are indolent and colonic NENs are rare among all GIT-NENs. Compared to colorectal adenocarcinoma neuroendocrine tumors of the colon and sigmoid colon are uncommon. Case outline. We present a 25-year-old female patient, who was admitted to our department in hemorrhagic shock due to life-threatening bleeding from a tumor on the sigmoid colon, and after unsuccessful endoscopic hemostasis during colonoscopy. The complaints started the day before admission to the ward with hematochezia. The patient had no complaints before that. Emergency operation and colon resection with terminal colostomy were performed. Pathohistological and immunohistochemical analysis of the tumor showed unclear histogenetic origin from the group of neuroendocrine tumors. Conclusion. Regardless of the asymptomatic period of the disease, these tumors can cause severe bleeding as the first symptom, which can be life-threatening. |
| first_indexed | 2024-03-11T23:34:23Z |
| format | Article |
| id | doaj.art-f76af671f0aa4d71a4fac756cd0bb492 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-03-11T23:34:23Z |
| publishDate | 2023-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-f76af671f0aa4d71a4fac756cd0bb4922023-09-20T06:03:11ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952023-01-011517-847247510.2298/SARH221212042Z0370-81792300042ZLarge Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shockZogić Enes0https://orcid.org/0000-0002-1355-3785Detanac Dženana A.1https://orcid.org/0000-0001-9225-6879Brničanin Kemal2Detanac Džemail S.3https://orcid.org/0000-0002-4823-5867Marovac Sead4Novi Pazar General Hospital, Novi Pazar, SerbiaNovi Pazar General Hospital, Novi Pazar, SerbiaNovi Pazar General Hospital, Novi Pazar, SerbiaNovi Pazar General Hospital, Novi Pazar, SerbiaNovi Pazar General Hospital, Novi Pazar, SerbiaIntroduction. Neuroendocrine neoplasms (NENs) of the gastrointestinal tract (GIT) are slow-growing and rare tumors with different clinical, histological, and biological characteristics with an increased incidence in recent years. Most of them are indolent and colonic NENs are rare among all GIT-NENs. Compared to colorectal adenocarcinoma neuroendocrine tumors of the colon and sigmoid colon are uncommon. Case outline. We present a 25-year-old female patient, who was admitted to our department in hemorrhagic shock due to life-threatening bleeding from a tumor on the sigmoid colon, and after unsuccessful endoscopic hemostasis during colonoscopy. The complaints started the day before admission to the ward with hematochezia. The patient had no complaints before that. Emergency operation and colon resection with terminal colostomy were performed. Pathohistological and immunohistochemical analysis of the tumor showed unclear histogenetic origin from the group of neuroendocrine tumors. Conclusion. Regardless of the asymptomatic period of the disease, these tumors can cause severe bleeding as the first symptom, which can be life-threatening.https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300042Z.pdfneuroendocrine neoplasmshemorrhagic shockcolon tumorssurgery |
| spellingShingle | Zogić Enes Detanac Dženana A. Brničanin Kemal Detanac Džemail S. Marovac Sead Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock Srpski Arhiv za Celokupno Lekarstvo neuroendocrine neoplasms hemorrhagic shock colon tumors surgery |
| title | Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock |
| title_full | Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock |
| title_fullStr | Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock |
| title_full_unstemmed | Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock |
| title_short | Large Bowel's tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life-threatening hemorrhage and hemorrhagic shock |
| title_sort | large bowel s tumor of unclear histogenetic origin from the group of neuroendocrine tumors with life threatening hemorrhage and hemorrhagic shock |
| topic | neuroendocrine neoplasms hemorrhagic shock colon tumors surgery |
| url | https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300042Z.pdf |
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