Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury
Background: We aimed to explore the diagnostic value of urinary microalbumin (mALB) level in postpartum acute kidney injury. Methods: A total of 127 maternity patients were selected from December 2013 to January in 2016 in Binzhou Central Hospital, Binzhou, Shandong, China and divided into two grou...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2018-03-01
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| Series: | Iranian Journal of Public Health |
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| Online Access: | https://ijph.tums.ac.ir/index.php/ijph/article/view/12683 |
| _version_ | 1818885763412000768 |
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| author | Jian ZHANG Ning LI Wenling GUO Chuanyan MA Guangcheng ZHAO |
| author_facet | Jian ZHANG Ning LI Wenling GUO Chuanyan MA Guangcheng ZHAO |
| author_sort | Jian ZHANG |
| collection | DOAJ |
| description | Background: We aimed to explore the diagnostic value of urinary microalbumin (mALB) level in postpartum acute kidney injury.
Methods: A total of 127 maternity patients were selected from December 2013 to January in 2016 in Binzhou Central Hospital, Binzhou, Shandong, China and divided into two groups: the kidney injury and normal kidney group. The dynamic changes and diagnostic value of urine microprotein in postpartum acute kidney injury were analyzed.
Results: The postpartum mean arterial pressure of maternity patients in the kidney injury group was 104.3 ± 11.6 mmHg, which was significantly higher than that of the normal kidney group (P<0.05). The mean age of the kidney injury group was 32.3 ± 11.6 years, which was significantly higher than that of the normal kidney group (P=0.006). In the kidney injury group, the postpartum glomerular filtration rate (GFR) was 78.4 ± 11.5 mL/min, which was significantly lower than the normal group (P=0.001), and urinary microalbumin was 2.87 ± 1.24 mg/mmol·Cr. The difference was statistically significant (P=0.002). mALB/GFR, Cr, urinary mALB, and GFR were the independent risk factors of postpartum acute kidney injury. The area under the ROC curve for mALB/GFR was 0.759, whereas the area under the ROC curve for Cr was 0.681, which was smaller (P = 0.042). The area under the ROC curve of mALB was 0.785 (P=0.027), which was close to the area under the ROC curve of mALB/GFR.
Conclusion: Urinary mALB test is noninvasive and has high diagnostic value for postpartum kidney injury. |
| first_indexed | 2024-12-19T16:10:37Z |
| format | Article |
| id | doaj.art-f76e55514be741b18eb8e248b9e15c20 |
| institution | Directory Open Access Journal |
| issn | 2251-6085 2251-6093 |
| language | English |
| last_indexed | 2024-12-19T16:10:37Z |
| publishDate | 2018-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-f76e55514be741b18eb8e248b9e15c202022-12-21T20:14:46ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932018-03-01473Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney InjuryJian ZHANG0Ning LI1Wenling GUO2Chuanyan MA3Guangcheng ZHAO4Dept. of Obstetrical, Binzhou Central Hospital, Binzhou, Shandong, ChinaDept. of Obstetrical, Binzhou Central Hospital, Binzhou, Shandong, ChinaDept. of Obstetrical, Binzhou Central Hospital, Binzhou, Shandong, ChinaDept. of Obstetrical, Binzhou Central Hospital, Binzhou, Shandong, ChinaDept. of Imaging, Binzhou Central Hospital, Binzhou, Shandong, ChinaBackground: We aimed to explore the diagnostic value of urinary microalbumin (mALB) level in postpartum acute kidney injury. Methods: A total of 127 maternity patients were selected from December 2013 to January in 2016 in Binzhou Central Hospital, Binzhou, Shandong, China and divided into two groups: the kidney injury and normal kidney group. The dynamic changes and diagnostic value of urine microprotein in postpartum acute kidney injury were analyzed. Results: The postpartum mean arterial pressure of maternity patients in the kidney injury group was 104.3 ± 11.6 mmHg, which was significantly higher than that of the normal kidney group (P<0.05). The mean age of the kidney injury group was 32.3 ± 11.6 years, which was significantly higher than that of the normal kidney group (P=0.006). In the kidney injury group, the postpartum glomerular filtration rate (GFR) was 78.4 ± 11.5 mL/min, which was significantly lower than the normal group (P=0.001), and urinary microalbumin was 2.87 ± 1.24 mg/mmol·Cr. The difference was statistically significant (P=0.002). mALB/GFR, Cr, urinary mALB, and GFR were the independent risk factors of postpartum acute kidney injury. The area under the ROC curve for mALB/GFR was 0.759, whereas the area under the ROC curve for Cr was 0.681, which was smaller (P = 0.042). The area under the ROC curve of mALB was 0.785 (P=0.027), which was close to the area under the ROC curve of mALB/GFR. Conclusion: Urinary mALB test is noninvasive and has high diagnostic value for postpartum kidney injury.https://ijph.tums.ac.ir/index.php/ijph/article/view/12683Postpartum acute kidney injuryUrinary microalbuminDiagnosis |
| spellingShingle | Jian ZHANG Ning LI Wenling GUO Chuanyan MA Guangcheng ZHAO Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury Iranian Journal of Public Health Postpartum acute kidney injury Urinary microalbumin Diagnosis |
| title | Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury |
| title_full | Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury |
| title_fullStr | Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury |
| title_full_unstemmed | Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury |
| title_short | Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury |
| title_sort | diagnostic value of urinary microalbumin level in postpartum acute kidney injury |
| topic | Postpartum acute kidney injury Urinary microalbumin Diagnosis |
| url | https://ijph.tums.ac.ir/index.php/ijph/article/view/12683 |
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