Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?

Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In...

Full description

Bibliographic Details
Main Author: Marieke L. Duiverman
Format: Article
Language:English
Published: European Respiratory Society 2018-04-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/4/2/00012-2018.full
_version_ 1811242054618972160
author Marieke L. Duiverman
author_facet Marieke L. Duiverman
author_sort Marieke L. Duiverman
collection DOAJ
description Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting the patients who might benefit most will be reviewed.
first_indexed 2024-04-12T13:46:15Z
format Article
id doaj.art-f7713fc2d22b46c5940332d1cd73359a
institution Directory Open Access Journal
issn 2312-0541
language English
last_indexed 2024-04-12T13:46:15Z
publishDate 2018-04-01
publisher European Respiratory Society
record_format Article
series ERJ Open Research
spelling doaj.art-f7713fc2d22b46c5940332d1cd73359a2022-12-22T03:30:40ZengEuropean Respiratory SocietyERJ Open Research2312-05412018-04-014210.1183/23120541.00012-201800012-2018Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?Marieke L. Duiverman0 Dept of Pulmonary Diseases/Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting the patients who might benefit most will be reviewed.http://openres.ersjournals.com/content/4/2/00012-2018.full
spellingShingle Marieke L. Duiverman
Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
ERJ Open Research
title Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
title_full Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
title_fullStr Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
title_full_unstemmed Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
title_short Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
title_sort noninvasive ventilation in stable hypercapnic copd what is the evidence
url http://openres.ersjournals.com/content/4/2/00012-2018.full
work_keys_str_mv AT mariekelduiverman noninvasiveventilationinstablehypercapniccopdwhatistheevidence