Current Role of Surgery in the Treatment of Neurocysticercosis
Neurocysticercosis (NCC) is a common parasitic disease of the central nervous system (CNS) in low- and middle-income countries. The infection is pleomorphic, caused by the larval form of the cestode, <i>Taenia solium</i>, and part of the heterogeneity of its clinical presentations is ass...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/13/3/218 |
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| author | Pedro Tadao Hamamoto Filho Luiz Fernando Norcia Agnès Fleury Marco Antônio Zanini |
| author_facet | Pedro Tadao Hamamoto Filho Luiz Fernando Norcia Agnès Fleury Marco Antônio Zanini |
| author_sort | Pedro Tadao Hamamoto Filho |
| collection | DOAJ |
| description | Neurocysticercosis (NCC) is a common parasitic disease of the central nervous system (CNS) in low- and middle-income countries. The infection is pleomorphic, caused by the larval form of the cestode, <i>Taenia solium</i>, and part of the heterogeneity of its clinical presentations is associated with the localization of the parasite within the CNS. Changes in the current epidemiological trends of NCC indicate that extra-parenchymal NCC is proportionally becoming more frequent. Extraparenchymal NCC is commonly accompanied by raised intracranial hypertension due to hydrocephalus, which is an emergency requiring cyst extirpation by surgical intervention to relieve the symptoms. Although less frequent, parenchymal cysts may also reach giant sizes requiring urgent surgical treatment. Finally, there is an advancement in the comprehension of the association between NCC and epilepsy—and patients with drug-resistant seizures are candidates for surgical treatment. In this narrative review, we summarize the present state of knowledge to update the current trends in the role of surgery in the treatment of NCC. |
| first_indexed | 2024-04-24T17:56:43Z |
| format | Article |
| id | doaj.art-f774e324e0724037acb6245cb829b205 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-04-24T17:56:43Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-f774e324e0724037acb6245cb829b2052024-03-27T13:58:52ZengMDPI AGPathogens2076-08172024-02-0113321810.3390/pathogens13030218Current Role of Surgery in the Treatment of NeurocysticercosisPedro Tadao Hamamoto Filho0Luiz Fernando Norcia1Agnès Fleury2Marco Antônio Zanini3Botucatu Medical School, UNESP—Universidade Estadual Paulista, Botucatu 18618-686, BrazilBotucatu Medical School, UNESP—Universidade Estadual Paulista, Botucatu 18618-686, BrazilInstituto de Investigaciones Biomedicas, UNAM—Universidad Nacional Autónoma de Mexico, Ciudad de Mexico 14269, MexicoBotucatu Medical School, UNESP—Universidade Estadual Paulista, Botucatu 18618-686, BrazilNeurocysticercosis (NCC) is a common parasitic disease of the central nervous system (CNS) in low- and middle-income countries. The infection is pleomorphic, caused by the larval form of the cestode, <i>Taenia solium</i>, and part of the heterogeneity of its clinical presentations is associated with the localization of the parasite within the CNS. Changes in the current epidemiological trends of NCC indicate that extra-parenchymal NCC is proportionally becoming more frequent. Extraparenchymal NCC is commonly accompanied by raised intracranial hypertension due to hydrocephalus, which is an emergency requiring cyst extirpation by surgical intervention to relieve the symptoms. Although less frequent, parenchymal cysts may also reach giant sizes requiring urgent surgical treatment. Finally, there is an advancement in the comprehension of the association between NCC and epilepsy—and patients with drug-resistant seizures are candidates for surgical treatment. In this narrative review, we summarize the present state of knowledge to update the current trends in the role of surgery in the treatment of NCC.https://www.mdpi.com/2076-0817/13/3/218neurocysticercosishydrocephalusintracranial pressureinflammationVP shuntneuro-endoscopy |
| spellingShingle | Pedro Tadao Hamamoto Filho Luiz Fernando Norcia Agnès Fleury Marco Antônio Zanini Current Role of Surgery in the Treatment of Neurocysticercosis Pathogens neurocysticercosis hydrocephalus intracranial pressure inflammation VP shunt neuro-endoscopy |
| title | Current Role of Surgery in the Treatment of Neurocysticercosis |
| title_full | Current Role of Surgery in the Treatment of Neurocysticercosis |
| title_fullStr | Current Role of Surgery in the Treatment of Neurocysticercosis |
| title_full_unstemmed | Current Role of Surgery in the Treatment of Neurocysticercosis |
| title_short | Current Role of Surgery in the Treatment of Neurocysticercosis |
| title_sort | current role of surgery in the treatment of neurocysticercosis |
| topic | neurocysticercosis hydrocephalus intracranial pressure inflammation VP shunt neuro-endoscopy |
| url | https://www.mdpi.com/2076-0817/13/3/218 |
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