Carboxylation of phenol and its derivatives with sodium ethyl carbonate
A comparison activity of phenol and its derivatives in carboxylation reaction with sodium ethyl carbonate was carried out (the ratio between substrate and sodium ethyl carbonate was 2:1, T=185°С, Pco2=10 atm, τ=7 h). p-Cresol, p-chlorophenol, phenol, m-cresol, p-fluorophenol, p-bromophenol, and m-ch...
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| Format: | Article |
| Language: | English |
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De Gruyter
2017-11-01
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| Series: | Green Processing and Synthesis |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/gps-2016-0116 |
| _version_ | 1818927280070590464 |
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| author | Suerbaev Khakim A. Aldabergenov Mayliby K. Kudaibergenov Nurbolat Zh. |
| author_facet | Suerbaev Khakim A. Aldabergenov Mayliby K. Kudaibergenov Nurbolat Zh. |
| author_sort | Suerbaev Khakim A. |
| collection | DOAJ |
| description | A comparison activity of phenol and its derivatives in carboxylation reaction with sodium ethyl carbonate was carried out (the ratio between substrate and sodium ethyl carbonate was 2:1, T=185°С, Pco2=10 atm, τ=7 h). p-Cresol, p-chlorophenol, phenol, m-cresol, p-fluorophenol, p-bromophenol, and m-chlorophenol showed the highest activity in this reaction. o-Cresol and o-chlorophenol showed moderate activity but 2,4-dichlorophenol did not enter into the reaction. The optimum conditions for the carboxylation reaction of phenol with sodium ethyl carbonate under microwave irradiation was determined (microwave irradiation power 450 W, duration 9 min; the ratio of the initial reagents, phenol, and sodium ethylcarbonate was 1.5:1). A comparison activity of phenol and its methyl- and halogen substituted derivatives in the carboxylation reaction with sodium ethyl carbonate under microwave irradiation was conducted. The reaction proceeded in accordance with the rule of electrophilic substitution reaction of aromatic compounds and, in all cases, went selectively into the o-position to form corresponding phenol carbonic acid derivatives with yields ranging from 6.8%–39.5%. |
| first_indexed | 2024-12-20T03:10:30Z |
| format | Article |
| id | doaj.art-f7786671879a47ee97eb8e6d6da5a030 |
| institution | Directory Open Access Journal |
| issn | 2191-9542 2191-9550 |
| language | English |
| last_indexed | 2024-12-20T03:10:30Z |
| publishDate | 2017-11-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Green Processing and Synthesis |
| spelling | doaj.art-f7786671879a47ee97eb8e6d6da5a0302022-12-21T19:55:29ZengDe GruyterGreen Processing and Synthesis2191-95422191-95502017-11-016654354710.1515/gps-2016-0116Carboxylation of phenol and its derivatives with sodium ethyl carbonateSuerbaev Khakim A.0Aldabergenov Mayliby K.1Kudaibergenov Nurbolat Zh.2Faculty of Chemistry and Chemical Technology, Al-Faraby Kazakh National University, Al-Farabi av, 71 Almaty 050038, The Republic of KazakhstanFaculty of Chemistry and Chemical Technology, Al-Faraby Kazakh National University, Almaty, The Republic of KazakhstanFaculty of Chemistry and Chemical Technology, Al-Faraby Kazakh National University, Almaty, The Republic of KazakhstanA comparison activity of phenol and its derivatives in carboxylation reaction with sodium ethyl carbonate was carried out (the ratio between substrate and sodium ethyl carbonate was 2:1, T=185°С, Pco2=10 atm, τ=7 h). p-Cresol, p-chlorophenol, phenol, m-cresol, p-fluorophenol, p-bromophenol, and m-chlorophenol showed the highest activity in this reaction. o-Cresol and o-chlorophenol showed moderate activity but 2,4-dichlorophenol did not enter into the reaction. The optimum conditions for the carboxylation reaction of phenol with sodium ethyl carbonate under microwave irradiation was determined (microwave irradiation power 450 W, duration 9 min; the ratio of the initial reagents, phenol, and sodium ethylcarbonate was 1.5:1). A comparison activity of phenol and its methyl- and halogen substituted derivatives in the carboxylation reaction with sodium ethyl carbonate under microwave irradiation was conducted. The reaction proceeded in accordance with the rule of electrophilic substitution reaction of aromatic compounds and, in all cases, went selectively into the o-position to form corresponding phenol carbonic acid derivatives with yields ranging from 6.8%–39.5%.https://doi.org/10.1515/gps-2016-0116carboxylationhydroxybenzoic acidsphenolssodium ethyl carbonate |
| spellingShingle | Suerbaev Khakim A. Aldabergenov Mayliby K. Kudaibergenov Nurbolat Zh. Carboxylation of phenol and its derivatives with sodium ethyl carbonate Green Processing and Synthesis carboxylation hydroxybenzoic acids phenols sodium ethyl carbonate |
| title | Carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| title_full | Carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| title_fullStr | Carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| title_full_unstemmed | Carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| title_short | Carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| title_sort | carboxylation of phenol and its derivatives with sodium ethyl carbonate |
| topic | carboxylation hydroxybenzoic acids phenols sodium ethyl carbonate |
| url | https://doi.org/10.1515/gps-2016-0116 |
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