The matrix reloaded – Addressing structural integrity of the aortic wall in aneurysmal disease

Thoracic aortic aneurysms and dissections (TAADs) involve dilation of the aortic wall that can lead to tearing or rupture. Progressive extracellular matrix (ECM) degradation is common in TAAD, regardless of the underlying cause. TAAD treatments typically target cellular signaling pathways, rather th...

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Bibliographic Details
Main Author: Jessica E. Wagenseil
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomaterials and Biosystems
Online Access:http://www.sciencedirect.com/science/article/pii/S2666534423000016

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