Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review Analysis of Studies on Palatable Food, Drugs of Abuse, and Alcohol

Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review Analysis of Studies on Palatable Food, Drugs of Abuse, and Alcohol

The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known; GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in diabetes. GLP-1 receptors (GLP-1R) are also widely expressed in the brain, and in addition to its role in neuroprotection, it affec...

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Bibliographic Details
Main Authors: Candan Yasemin Eren-Yazicioglu, Arya Yigit, Ramazan Efe Dogruoz, Hale Yapici-Eser
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
GLP-1
reward
food intake
mood
cocaine
amphetamine
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2020.614884/full

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