Protective Effect of N-Acetylcysteine Amide on Blast-Induced Increase in Intracranial Pressure in Rats

Protective Effect of N-Acetylcysteine Amide on Blast-Induced Increase in Intracranial Pressure in Rats

Blast-induced traumatic brain injury is associated with acute and possibly chronic elevation of intracranial pressure (ICP). The outcome after TBI is dependent on the progression of complex processes which are mediated by oxidative stress. So far, no effective pharmacological protection against TBI...

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Bibliographic Details
Main Authors: Usmah Kawoos, Richard M. McCarron, Mikulas Chavko
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Neurology
Subjects:
blast overpressure
traumatic brain injury
intracranial pressure
oxidative stress
N-acetylcysteine amide
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00219/full

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