Osteoporosis: From Molecular Mechanisms to Therapies 2.0
Osteoporosis is a common skeletal disorder, occurring as a result of an imbalance between bone resorption and bone formation, with bone breakdown exceeding bone building. Bone resorption inhibitors, e.g., bisphosphonates, have been designed to treat osteoporosis. Teriparatide, an anabolic agent, sti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/21/8005 |
| _version_ | 1797549637652971520 |
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| author | Chih-Hsin Tang |
| author_facet | Chih-Hsin Tang |
| author_sort | Chih-Hsin Tang |
| collection | DOAJ |
| description | Osteoporosis is a common skeletal disorder, occurring as a result of an imbalance between bone resorption and bone formation, with bone breakdown exceeding bone building. Bone resorption inhibitors, e.g., bisphosphonates, have been designed to treat osteoporosis. Teriparatide, an anabolic agent, stimulates bone formation and corrects the characteristic changes in the trabecular microarchitecture. However, these drugs are associated with significant side effects. It is therefore crucial that we continue to research the pathogenesis of osteoporosis and seek novel modes of therapy. This editorial summarizes and discusses the themes of the ten articles published in our Special Issue “Osteoporosis: From Molecular Mechanisms to Therapies 2.0”, a continuation of our 2019 Special Issue "Osteoporosis: From Molecular Mechanisms to Therapies" (https://www.mdpi.com/journal/ijms/special_issues/osteoporosis_ijms). These Special Issues detail important global scientific findings that contribute to our current understanding of osteoporosis. |
| first_indexed | 2024-03-10T15:18:22Z |
| format | Article |
| id | doaj.art-f783509cb85143daab6cc6dec95f157a |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T15:18:22Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-f783509cb85143daab6cc6dec95f157a2023-11-20T18:47:30ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-10-012121800510.3390/ijms21218005Osteoporosis: From Molecular Mechanisms to Therapies 2.0Chih-Hsin Tang0Department of Pharmacology, School of Medicine, China Medical University, Taichung 404, TaiwanOsteoporosis is a common skeletal disorder, occurring as a result of an imbalance between bone resorption and bone formation, with bone breakdown exceeding bone building. Bone resorption inhibitors, e.g., bisphosphonates, have been designed to treat osteoporosis. Teriparatide, an anabolic agent, stimulates bone formation and corrects the characteristic changes in the trabecular microarchitecture. However, these drugs are associated with significant side effects. It is therefore crucial that we continue to research the pathogenesis of osteoporosis and seek novel modes of therapy. This editorial summarizes and discusses the themes of the ten articles published in our Special Issue “Osteoporosis: From Molecular Mechanisms to Therapies 2.0”, a continuation of our 2019 Special Issue "Osteoporosis: From Molecular Mechanisms to Therapies" (https://www.mdpi.com/journal/ijms/special_issues/osteoporosis_ijms). These Special Issues detail important global scientific findings that contribute to our current understanding of osteoporosis.https://www.mdpi.com/1422-0067/21/21/8005osteoporosistreatmentpreventionmolecular mechanismssignaling pathway |
| spellingShingle | Chih-Hsin Tang Osteoporosis: From Molecular Mechanisms to Therapies 2.0 International Journal of Molecular Sciences osteoporosis treatment prevention molecular mechanisms signaling pathway |
| title | Osteoporosis: From Molecular Mechanisms to Therapies 2.0 |
| title_full | Osteoporosis: From Molecular Mechanisms to Therapies 2.0 |
| title_fullStr | Osteoporosis: From Molecular Mechanisms to Therapies 2.0 |
| title_full_unstemmed | Osteoporosis: From Molecular Mechanisms to Therapies 2.0 |
| title_short | Osteoporosis: From Molecular Mechanisms to Therapies 2.0 |
| title_sort | osteoporosis from molecular mechanisms to therapies 2 0 |
| topic | osteoporosis treatment prevention molecular mechanisms signaling pathway |
| url | https://www.mdpi.com/1422-0067/21/21/8005 |
| work_keys_str_mv | AT chihhsintang osteoporosisfrommolecularmechanismstotherapies20 |