GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

Abstract Background The complex pathophysiology of epilepsy hampers the development of effective treatments. Although more than ten kinds of anti-seizures drugs (ASDs) have good effects on seizure control worldwide, about 30% of patients still display pharmacoresistance against ASDs. Neuroinflammati...

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Bibliographic Details
Main Authors: Zhangjin Qin, Jiaqi Song, Aolei Lin, Wei Yang, Wenbo Zhang, Fuxin Zhong, Lihong Huang, Yang Lü, Weihua Yu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Neuroinflammation
Subjects:
GPR120
Neuroinflammation
NLRP3 inflammasome
Epilepsy
Neuronal damage
Online Access:https://doi.org/10.1186/s12974-022-02482-2

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