Silane Modification of Mesoporous Materials for the Optimization of Antiviral Drug Adsorption and Release Capabilities in Vaginal Media

Silane Modification of Mesoporous Materials for the Optimization of Antiviral Drug Adsorption and Release Capabilities in Vaginal Media

Three different functionalities have been incorporated into mesoporous materials by means of a coupling reaction with the siloxanes 3-glycidoxypropyl-trimethoxysilane (GLYMO), 3-methacryloxypropyl-trimethoxysilane (MEMO), and 3-mercaptopropyl-trimethoxysilane (MPTMS). The disposition of the differen...

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Bibliographic Details
Main Authors: Elena Whittle, Araceli Martín-Illana, Raul Cazorla-Luna, Fernando Notario-Perez, María Dolores Veiga-Ochoa, Juan Rubio, Aitana Tamayo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
organic–inorganic hybrid
drug delivery
antiviral
acyclovir
Online Access:https://www.mdpi.com/1999-4923/13/9/1416

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