A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species

The genus Cymbopogon belongs to Poaceae family and contain about 54 species, commonly known as "lemongrass". Cymbopogon is a medicinal plant native to tropical and subtropical areas which is applied traditionally for its numerous properties including antirheumatic, antispasmodic, analgesic...

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Main Authors: Soodeh Karami, Alireza Yargholi, Seyede Nargess Sadati Lamardi, Samaneh Soleymani, Laila Shirbeigi, Roja Rahimi*
Format: Article
Language:English
Published: Iranian Society of Pharmacognosy 2021-06-01
Series:Research Journal of Pharmacognosy
Subjects:
Online Access:http://www.rjpharmacognosy.ir/article_131366_7830a32b73b821e5efcd9c6c7757b77c.pdf
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author Soodeh Karami
Alireza Yargholi
Seyede Nargess Sadati Lamardi
Samaneh Soleymani
Laila Shirbeigi
Roja Rahimi*
author_facet Soodeh Karami
Alireza Yargholi
Seyede Nargess Sadati Lamardi
Samaneh Soleymani
Laila Shirbeigi
Roja Rahimi*
author_sort Soodeh Karami
collection DOAJ
description The genus Cymbopogon belongs to Poaceae family and contain about 54 species, commonly known as "lemongrass". Cymbopogon is a medicinal plant native to tropical and subtropical areas which is applied traditionally for its numerous properties including antirheumatic, antispasmodic, analgesic, antiseptic, hypotensive, antitussive and anticonvulsant ctivities, and as a treatment for gastrointestinal and nervous disorders and fever. The aims of this study were to discuss about current state of phytochemistry, pharmacology, and pharmacological effects of different species of Cymbopogon. Electronic databases including PubMed, Scopus, Cochrane library and Google Scholar were searched with the scientific name and the common name of the plant until November 2019. In spite of the small number of clinical investigations, Cymbopogon genus is widely evaluated for its phytochemistry, ethnopharmacology and biological activities. Monoterpenes specially geranial, citronellol and citral are the chief components of the essential oil. Biological activities including antioxidant, antibacterial, antiviral, insecticidal, anticancer, hepatoprotective activities as well as its effect on skin, urogenital, gastrointestinal, neuropsychological and cardiovascular systems are proved in cell lines and animal models. Extensive studies have been done on various biological activities of lemongrass; nevertheless, safety and efficacy of Cymbopogon species are not fully evaluated in human and further well-designed clinical trials are required to confirm preclinical findings.
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spelling doaj.art-f789f84e1e5e49acb791ac0a3793adca2022-12-21T20:21:27ZengIranian Society of PharmacognosyResearch Journal of Pharmacognosy2345-44582345-59772021-06-01838311210.22127/rjp.2021.275223.1682131366A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon SpeciesSoodeh Karami0Alireza Yargholi1Seyede Nargess Sadati Lamardi2Samaneh Soleymani3Laila Shirbeigi4Roja Rahimi*5Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Persian Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Persian Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.The genus Cymbopogon belongs to Poaceae family and contain about 54 species, commonly known as "lemongrass". Cymbopogon is a medicinal plant native to tropical and subtropical areas which is applied traditionally for its numerous properties including antirheumatic, antispasmodic, analgesic, antiseptic, hypotensive, antitussive and anticonvulsant ctivities, and as a treatment for gastrointestinal and nervous disorders and fever. The aims of this study were to discuss about current state of phytochemistry, pharmacology, and pharmacological effects of different species of Cymbopogon. Electronic databases including PubMed, Scopus, Cochrane library and Google Scholar were searched with the scientific name and the common name of the plant until November 2019. In spite of the small number of clinical investigations, Cymbopogon genus is widely evaluated for its phytochemistry, ethnopharmacology and biological activities. Monoterpenes specially geranial, citronellol and citral are the chief components of the essential oil. Biological activities including antioxidant, antibacterial, antiviral, insecticidal, anticancer, hepatoprotective activities as well as its effect on skin, urogenital, gastrointestinal, neuropsychological and cardiovascular systems are proved in cell lines and animal models. Extensive studies have been done on various biological activities of lemongrass; nevertheless, safety and efficacy of Cymbopogon species are not fully evaluated in human and further well-designed clinical trials are required to confirm preclinical findings.http://www.rjpharmacognosy.ir/article_131366_7830a32b73b821e5efcd9c6c7757b77c.pdfcitraldiabetes mellitushyperlipidemiainflammationlemongrass
spellingShingle Soodeh Karami
Alireza Yargholi
Seyede Nargess Sadati Lamardi
Samaneh Soleymani
Laila Shirbeigi
Roja Rahimi*
A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
Research Journal of Pharmacognosy
citral
diabetes mellitus
hyperlipidemia
inflammation
lemongrass
title A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
title_full A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
title_fullStr A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
title_full_unstemmed A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
title_short A Review of Ethnopharmacology, Phytochemistry and Pharmacology of Cymbopogon Species
title_sort review of ethnopharmacology phytochemistry and pharmacology of cymbopogon species
topic citral
diabetes mellitus
hyperlipidemia
inflammation
lemongrass
url http://www.rjpharmacognosy.ir/article_131366_7830a32b73b821e5efcd9c6c7757b77c.pdf
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