Current Status and Future Prospects in Herbicide Discovery
Herbicides represent about 60% of the pesticides (by volume) used worldwide. The success of herbicides can be attributed in part to a relatively steady discovery of one unique mechanisms of action (MOA) every two years from the early 1950s to the mid-1980s. While this situation changed dramatically...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-09-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/8/9/341 |
| _version_ | 1818085254295977984 |
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| author | Franck E. Dayan |
| author_facet | Franck E. Dayan |
| author_sort | Franck E. Dayan |
| collection | DOAJ |
| description | Herbicides represent about 60% of the pesticides (by volume) used worldwide. The success of herbicides can be attributed in part to a relatively steady discovery of one unique mechanisms of action (MOA) every two years from the early 1950s to the mid-1980s. While this situation changed dramatically after the introduction of glyphosate-resistant crops, evolution of resistance to glyphosate has renewed the agrichemical industry interest in new chemistry interacting with novel target sites. This review analyses recent characterization of new herbicide target sites, the chemical classes developed to inhibit these target sites, and where appropriate the innovative technologies used in these discovery programs. |
| first_indexed | 2024-12-10T20:06:52Z |
| format | Article |
| id | doaj.art-f78ab1e68c444764b2bef3939e1675ec |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-12-10T20:06:52Z |
| publishDate | 2019-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-f78ab1e68c444764b2bef3939e1675ec2022-12-22T01:35:22ZengMDPI AGPlants2223-77472019-09-018934110.3390/plants8090341plants8090341Current Status and Future Prospects in Herbicide DiscoveryFranck E. Dayan0Department of Bioagricultural Sciences and Pest Management, 1177 Campus Delivery, Colorado State University, Fort Collins, CO 80523, USAHerbicides represent about 60% of the pesticides (by volume) used worldwide. The success of herbicides can be attributed in part to a relatively steady discovery of one unique mechanisms of action (MOA) every two years from the early 1950s to the mid-1980s. While this situation changed dramatically after the introduction of glyphosate-resistant crops, evolution of resistance to glyphosate has renewed the agrichemical industry interest in new chemistry interacting with novel target sites. This review analyses recent characterization of new herbicide target sites, the chemical classes developed to inhibit these target sites, and where appropriate the innovative technologies used in these discovery programs.https://www.mdpi.com/2223-7747/8/9/341amino acid biosynthesislipid biosynthesismechanism of actionplastoquinone biosynthesispyrimidine biosynthesistarget site |
| spellingShingle | Franck E. Dayan Current Status and Future Prospects in Herbicide Discovery Plants amino acid biosynthesis lipid biosynthesis mechanism of action plastoquinone biosynthesis pyrimidine biosynthesis target site |
| title | Current Status and Future Prospects in Herbicide Discovery |
| title_full | Current Status and Future Prospects in Herbicide Discovery |
| title_fullStr | Current Status and Future Prospects in Herbicide Discovery |
| title_full_unstemmed | Current Status and Future Prospects in Herbicide Discovery |
| title_short | Current Status and Future Prospects in Herbicide Discovery |
| title_sort | current status and future prospects in herbicide discovery |
| topic | amino acid biosynthesis lipid biosynthesis mechanism of action plastoquinone biosynthesis pyrimidine biosynthesis target site |
| url | https://www.mdpi.com/2223-7747/8/9/341 |
| work_keys_str_mv | AT franckedayan currentstatusandfutureprospectsinherbicidediscovery |