Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice

Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice

Myocardial infarction is the major cause of death in cardiovascular disease. In vitro and in vivo models are used to find the exercise mode which has the most significant effect on myocardial irisin/FNDC5 expression and illuminate the cardioprotective role and mechanisms of exercise-activated myocar...

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Bibliographic Details
Main Authors: Hangzhuo Li, Shuguang Qin, Qiaoqin Liang, Yue Xi, Wenyan Bo, Mengxin Cai, Zhenjun Tian
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
exercise training
myocardial infarction
mice
mitophagy
irisin
Online Access:https://www.mdpi.com/2227-9059/9/6/701

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