Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications
Recently, Mg-Zn/hydroxyapatite (HA) composites have attracted much attention as potential candidates for use in bone implants. In this paper, the MgZn/HA composites were prepared using powder metallurgy (PM) and the merging mechanism of MgZn and HA particles was investigated by adjusting the weight...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/16/16/5669 |
| _version_ | 1797584000220397568 |
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| author | Wei Lu Yinling Zhang Taolei Wang |
| author_facet | Wei Lu Yinling Zhang Taolei Wang |
| author_sort | Wei Lu |
| collection | DOAJ |
| description | Recently, Mg-Zn/hydroxyapatite (HA) composites have attracted much attention as potential candidates for use in bone implants. In this paper, the MgZn/HA composites were prepared using powder metallurgy (PM) and the merging mechanism of MgZn and HA particles was investigated by adjusting the weight ratio of the HA powder. The evolution of the HA distribution in the matrix was examined using SEM and micro-CT images. Afterward, the mechanical properties and biocompatibility of the composites were discussed in detail. The results revealed that the mechanical properties and biocompatibility of the Mg-Zn/HA composites were significantly affected by the HA content. Composites with a low HA content showed increased porosity, improved mechanical strength, and enhanced corrosion resistance after ball milling and cold pressing. These results underscore the importance of optimizing the HA content in Mg-Zn/HA composites for bone implants. Based on our findings, PM Mg-Zn/HA composites with a moderate HA content demonstrate the most promising characteristics as bone implants. The insights gained from this work contribute to the advancement of bone implant materials and hold great potential for enhancing orthopedic surgery outcomes. |
| first_indexed | 2024-03-10T23:47:03Z |
| format | Article |
| id | doaj.art-f78d6c72047945219b243b69a2bc8e16 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T23:47:03Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-f78d6c72047945219b243b69a2bc8e162023-11-19T02:01:01ZengMDPI AGMaterials1996-19442023-08-011616566910.3390/ma16165669Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant ApplicationsWei Lu0Yinling Zhang1Taolei Wang2School of Material Science and Engineering, Tongji University, Shanghai 201209, ChinaSchool of Mechanical Engineering, Shandong University of Technology, Zibo 255049, ChinaSchool of Mechanical Engineering, Suzhou University of Science and Technology, Suzhou 215009, ChinaRecently, Mg-Zn/hydroxyapatite (HA) composites have attracted much attention as potential candidates for use in bone implants. In this paper, the MgZn/HA composites were prepared using powder metallurgy (PM) and the merging mechanism of MgZn and HA particles was investigated by adjusting the weight ratio of the HA powder. The evolution of the HA distribution in the matrix was examined using SEM and micro-CT images. Afterward, the mechanical properties and biocompatibility of the composites were discussed in detail. The results revealed that the mechanical properties and biocompatibility of the Mg-Zn/HA composites were significantly affected by the HA content. Composites with a low HA content showed increased porosity, improved mechanical strength, and enhanced corrosion resistance after ball milling and cold pressing. These results underscore the importance of optimizing the HA content in Mg-Zn/HA composites for bone implants. Based on our findings, PM Mg-Zn/HA composites with a moderate HA content demonstrate the most promising characteristics as bone implants. The insights gained from this work contribute to the advancement of bone implant materials and hold great potential for enhancing orthopedic surgery outcomes.https://www.mdpi.com/1996-1944/16/16/5669magnesium alloysPMhydroxyapatitebone implants |
| spellingShingle | Wei Lu Yinling Zhang Taolei Wang Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications Materials magnesium alloys PM hydroxyapatite bone implants |
| title | Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications |
| title_full | Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications |
| title_fullStr | Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications |
| title_full_unstemmed | Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications |
| title_short | Microstructure, Mechanical Properties, In Vitro Biodegradability, and Biocompatibility of Mg-Zn/HA Composites for Biomedical Implant Applications |
| title_sort | microstructure mechanical properties in vitro biodegradability and biocompatibility of mg zn ha composites for biomedical implant applications |
| topic | magnesium alloys PM hydroxyapatite bone implants |
| url | https://www.mdpi.com/1996-1944/16/16/5669 |
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