Leukocyte Telomere Length Is Not Reduced in Children and Adults with Cystic Fibrosis but Associates with Clinical Characteristics—A Cross-Sectional Study

Leukocyte Telomere Length Is Not Reduced in Children and Adults with Cystic Fibrosis but Associates with Clinical Characteristics—A Cross-Sectional Study

We hypothezied that telomere length is considerably altered in cystic fibrosis (CF) patients compared to healthy subjects (HS), and that leukocyte telomere length variation reflects the severity of CF. Relative telomere length (RTL) was assessed by qPCR in 70 children aged 5–10 (34 CF; 36 HS) and 11...

Full description

Bibliographic Details
Main Authors: Aleksandra Glapa-Nowak, Shivaprakash Jagalur Mutt, Aleksandra Lisowska, Ewa Sapiejka, Joanna Goździk-Spychalska, Mirosława Wieczorek-Filipiak, Sławomira Drzymała-Czyż, Jan Krzysztof Nowak, Olaf Thalmann, Karl-Heinz Herzig, Jarosław Walkowiak
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
CFTR
dried blood spots
inhaled corticosteroids
<i>Pseudomonas aeruginosa</i>
pancreatic insufficiency
Online Access:https://www.mdpi.com/2077-0383/10/4/590

Internet

https://www.mdpi.com/2077-0383/10/4/590

Similar Items