Very late stent thrombosis of Sirolimus-eluting stent 59 months after implantation: A first report from the Middle-East and review of literature

Very late stent thrombosis occurs more frequently with drug-eluting stents and tends to occur despite dual antiplatelet therapy or after long periods of clopidogrel discontinuation. Stent thrombosis commonly presents with myocardial infarction or death. We report a 41-year-old Arab male with very la...

Full description

Bibliographic Details
Main Authors: Prashanth Panduranga, Mohammed Al-Mukhaini
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Heart Views
Subjects:
Online Access:http://www.heartviews.org/article.asp?issn=1995-705X;year=2011;volume=12;issue=1;spage=22;epage=25;aulast=Panduranga
Description
Summary:Very late stent thrombosis occurs more frequently with drug-eluting stents and tends to occur despite dual antiplatelet therapy or after long periods of clopidogrel discontinuation. Stent thrombosis commonly presents with myocardial infarction or death. We report a 41-year-old Arab male with very late stent thrombosis after 59 months of sirolimus-eluting stent implantation and -49 months after clopidogrel discontinuation despite aspirin continuation, presenting with exertional angina. He underwent successful percutaneous coronary intervention. This case underlines the need for novel stent designs as well as newer therapeutic strategies in preventing very late stent thrombosis among patients receiving drug-eluting stents.
ISSN:1995-705X