GM1 ganglioside-independent intoxication by Cholera toxin.

GM1 ganglioside-independent intoxication by Cholera toxin.

Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors via its B subunit (CTB). We have recently shown that in addition to the previously described binding partner ganglioside GM1, CTB binds to fucosylated proteins. Using flow cytometric analysis of primary human j...

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Bibliographic Details
Main Authors: Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006862

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