NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

<p>Abstract</p> <p>In effector T and B cells immune receptor signals induce within minutes a rise of intracellular Ca<sup>++</sup>, the activation of the phosphatase calcineurin and the translocation of NFAT transcription factors from cytosol to nucleus. In addition to...

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Bibliographic Details
Main Authors: Serfling Edgar, Avots Andris, Klein-Hessling Stefan, Rudolf Ronald, Vaeth Martin, Berberich-Siebelt Friederike
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Cell Communication and Signaling
Subjects:
Activation induced cell death/AICD
Anergy
Apoptosis
Calcineurin
NFATc
NFATc1/αA
NF-κB
Proliferation
Online Access:http://www.biosignaling.com/content/10/1/16

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