Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays
Background: Some evidence shows that a pre-exposure to RF can mitigate the effects of subsequent exposures to high doses of ionizing radiation.Objective: We aimed to assess the effect of a pre-exposure to non-ionizing RF radiation on survival, weight changes, food consumption, and water intake of le...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2022-10-01
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| Series: | Journal of Biomedical Physics and Engineering |
| Subjects: | |
| Online Access: | https://jbpe.sums.ac.ir/article_46905_63c79737f5a7526875103e163b24562d.pdf |
| _version_ | 1811336484817469440 |
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| author | Sajad Borzoueisileh Ali Shabestani Monfared Seyed Mohammad Javad Mortazavi Ebrahim Zabihi Mehdi Pouramir Fatemeh Niksirat Nayer Seyfizadeh Mohsen Shafiee |
| author_facet | Sajad Borzoueisileh Ali Shabestani Monfared Seyed Mohammad Javad Mortazavi Ebrahim Zabihi Mehdi Pouramir Fatemeh Niksirat Nayer Seyfizadeh Mohsen Shafiee |
| author_sort | Sajad Borzoueisileh |
| collection | DOAJ |
| description | Background: Some evidence shows that a pre-exposure to RF can mitigate the effects of subsequent exposures to high doses of ionizing radiation.Objective: We aimed to assess the effect of a pre-exposure to non-ionizing RF radiation on survival, weight changes, food consumption, and water intake of lethally irradiated rats.Material and Methods: In this case-control study, we used a commercial mobile phone (GSM, 900/1800 MHz) as well as a 2.4 GHz Wi-Fi router as the sources of pre-exposure to RF radiation. Forty-eight rats were randomly divided into six groups of control, “8 Gy X-rays”, mobile phone, “mobile phone+8 Gy”, Wi-Fi, and “Wi-Fi+8 Gy”. Then, the survival fraction, weight loss, water, and food consumption changes were compared in different groups.Results: The survival analysis indicated that the survival rates in all of the exposed animals (“8 Gy X-rays”, “mobile phone+8 Gy”, “Wi-Fi+8 Gy”) were significantly lower than the control, “Wi-Fi”, and “mobile phone” groups. The changes in survival rates of “mobile+8 Gy”, “Wi-Fi+8 Gy”, and 8 Gy alone were not statistically significant. However, food and water intake were significantly affected by exposure to both RF pre-exposures and exposure to high dose ionizing radiation. Conclusion: To the best of our knowledge, the existence of a dose window for the induction of AR can be the cause of the lack of AR in our experiment. Our findings confirm that in a similar pattern with the adaptive responses induced by pre-exposure to ionizing radiation, the induction of adaptive response by RF-pre-exposures requires a minimum level of damage to trigger adaptive phenomena. |
| first_indexed | 2024-04-13T17:40:11Z |
| format | Article |
| id | doaj.art-f79b1d45c1f846bc9d8b15e3964ee50b |
| institution | Directory Open Access Journal |
| issn | 2251-7200 |
| language | English |
| last_indexed | 2024-04-13T17:40:11Z |
| publishDate | 2022-10-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Biomedical Physics and Engineering |
| spelling | doaj.art-f79b1d45c1f846bc9d8b15e3964ee50b2022-12-22T02:37:13ZengShiraz University of Medical SciencesJournal of Biomedical Physics and Engineering2251-72002022-10-0112550551210.31661/jbpe.v0i0.127146905Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-RaysSajad Borzoueisileh0Ali Shabestani Monfared1Seyed Mohammad Javad Mortazavi2Ebrahim Zabihi3Mehdi Pouramir4Fatemeh Niksirat5Nayer Seyfizadeh6Mohsen Shafiee7MSc, Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranPhD, Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranPhD, Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPhD, Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranPhD, Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranMSc, Department of Medical Physics Radiobiology and Radiation Protection, School of Medicine, Babol University of Medical Sciences, Babol, IranPhD, Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, IranMSc, Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, IranBackground: Some evidence shows that a pre-exposure to RF can mitigate the effects of subsequent exposures to high doses of ionizing radiation.Objective: We aimed to assess the effect of a pre-exposure to non-ionizing RF radiation on survival, weight changes, food consumption, and water intake of lethally irradiated rats.Material and Methods: In this case-control study, we used a commercial mobile phone (GSM, 900/1800 MHz) as well as a 2.4 GHz Wi-Fi router as the sources of pre-exposure to RF radiation. Forty-eight rats were randomly divided into six groups of control, “8 Gy X-rays”, mobile phone, “mobile phone+8 Gy”, Wi-Fi, and “Wi-Fi+8 Gy”. Then, the survival fraction, weight loss, water, and food consumption changes were compared in different groups.Results: The survival analysis indicated that the survival rates in all of the exposed animals (“8 Gy X-rays”, “mobile phone+8 Gy”, “Wi-Fi+8 Gy”) were significantly lower than the control, “Wi-Fi”, and “mobile phone” groups. The changes in survival rates of “mobile+8 Gy”, “Wi-Fi+8 Gy”, and 8 Gy alone were not statistically significant. However, food and water intake were significantly affected by exposure to both RF pre-exposures and exposure to high dose ionizing radiation. Conclusion: To the best of our knowledge, the existence of a dose window for the induction of AR can be the cause of the lack of AR in our experiment. Our findings confirm that in a similar pattern with the adaptive responses induced by pre-exposure to ionizing radiation, the induction of adaptive response by RF-pre-exposures requires a minimum level of damage to trigger adaptive phenomena.https://jbpe.sums.ac.ir/article_46905_63c79737f5a7526875103e163b24562d.pdfradiofrequency radiation (rf)radioadaptive responsecell phoneelectromagnetic radiationsurvival analysis |
| spellingShingle | Sajad Borzoueisileh Ali Shabestani Monfared Seyed Mohammad Javad Mortazavi Ebrahim Zabihi Mehdi Pouramir Fatemeh Niksirat Nayer Seyfizadeh Mohsen Shafiee Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays Journal of Biomedical Physics and Engineering radiofrequency radiation (rf) radioadaptive response cell phone electromagnetic radiation survival analysis |
| title | Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays |
| title_full | Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays |
| title_fullStr | Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays |
| title_full_unstemmed | Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays |
| title_short | Pre-Exposure to Radiofrequency Electromagnetic Fields and Induction of Radioadaptive Response in Rats Irradiated with High Doses of X-Rays |
| title_sort | pre exposure to radiofrequency electromagnetic fields and induction of radioadaptive response in rats irradiated with high doses of x rays |
| topic | radiofrequency radiation (rf) radioadaptive response cell phone electromagnetic radiation survival analysis |
| url | https://jbpe.sums.ac.ir/article_46905_63c79737f5a7526875103e163b24562d.pdf |
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