Tadalafil Treatment of Mice with Fetal Growth Restriction and Preeclampsia Improves Placental mTOR Signaling

Tadalafil Treatment of Mice with Fetal Growth Restriction and Preeclampsia Improves Placental mTOR Signaling

Fetal growth restriction (FGR) is a major cause of poor perinatal outcomes. Although several studies have been conducted to improve the prognosis of FGR in infants, no effective intrauterine treatment method has been established. This study aimed to use tadalafil, a phosphodiesterase 5 inhibitor (PD...

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Bibliographic Details
Main Authors: Kayo Tanaka, Hiroaki Tanaka, Ryota Tachibana, Kento Yoshikawa, Takuya Kawamura, Sho Takakura, Hiroki Takeuchi, Tomoaki Ikeda
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
fetal growth restriction
placenta
mTOR signaling
tadalafil
preeclampsia
L-NAME
Online Access:https://www.mdpi.com/1422-0067/23/3/1474

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