Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia wit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/2/368 |
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| author | Melinda Ildiko Mitranovici Ioan Emilian Oală Izabella Petre Marius Lucian Craina Silviana Narcisa Floruț Diana Maria Chiorean Iuliu Gabriel Cocuz Sabin Gligore Turdean Ovidiu Simion Cotoi Lucian Pușcașiu |
| author_facet | Melinda Ildiko Mitranovici Ioan Emilian Oală Izabella Petre Marius Lucian Craina Silviana Narcisa Floruț Diana Maria Chiorean Iuliu Gabriel Cocuz Sabin Gligore Turdean Ovidiu Simion Cotoi Lucian Pușcașiu |
| author_sort | Melinda Ildiko Mitranovici |
| collection | DOAJ |
| description | Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies. |
| first_indexed | 2024-03-09T22:11:53Z |
| format | Article |
| id | doaj.art-f7a6d174a98d450da8f0fab1ddd0cf38 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T22:11:53Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-f7a6d174a98d450da8f0fab1ddd0cf382023-11-23T19:30:51ZengMDPI AGDiagnostics2075-44182022-02-0112236810.3390/diagnostics12020368Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and UpdateMelinda Ildiko Mitranovici0Ioan Emilian Oală1Izabella Petre2Marius Lucian Craina3Silviana Narcisa Floruț4Diana Maria Chiorean5Iuliu Gabriel Cocuz6Sabin Gligore Turdean7Ovidiu Simion Cotoi8Lucian Pușcașiu9Department of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, RomaniaDepartment of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, RomaniaDepartment of Obstetrics and Gynecology, Victor Babeș University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, RomaniaDepartment of Obstetrics and Gynecology, Victor Babeș University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, RomaniaDepartment of Pathology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, RomaniaDepartment of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, RomaniaDepartment of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, RomaniaDepartment of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, RomaniaDepartment of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, RomaniaDepartment of Obstetrics, Gynecology County Emergency Hospital, University of Medicine and Pharmacty Targu Mures, 38 Gh. Marinescu Str., 540142 Targu Mures, RomaniaAtypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies.https://www.mdpi.com/2075-4418/12/2/368atypical polypoid adenomyomaatypical endometrial hyperplasiacarcinosarcomatotal hysterectomy with bilateral salpingo-oophorectomytumor resection |
| spellingShingle | Melinda Ildiko Mitranovici Ioan Emilian Oală Izabella Petre Marius Lucian Craina Silviana Narcisa Floruț Diana Maria Chiorean Iuliu Gabriel Cocuz Sabin Gligore Turdean Ovidiu Simion Cotoi Lucian Pușcașiu Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update Diagnostics atypical polypoid adenomyoma atypical endometrial hyperplasia carcinosarcoma total hysterectomy with bilateral salpingo-oophorectomy tumor resection |
| title | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
| title_full | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
| title_fullStr | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
| title_full_unstemmed | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
| title_short | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
| title_sort | atypical polypoid adenomyoma of the vagina follow up and subsequent evolution a case report and update |
| topic | atypical polypoid adenomyoma atypical endometrial hyperplasia carcinosarcoma total hysterectomy with bilateral salpingo-oophorectomy tumor resection |
| url | https://www.mdpi.com/2075-4418/12/2/368 |
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