INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY
In patients with myocardial infarction, the dynamics of acute phase proteins (APP), oxidative stress and white blood cell functional activity was investigated. A statistically significant increase in APP levels was observed starting from Day 1, reached its peak at Day 7, and disappeared by Day 28. A...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2009-10-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1383 |
| _version_ | 1797857192702902272 |
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| author | I. I. Chukaeva N. V. Orlova F. A. Evdokimov V. A. Aleshkin O. O. Soloshenkova L. I. Novikova N. P. Rechnova |
| author_facet | I. I. Chukaeva N. V. Orlova F. A. Evdokimov V. A. Aleshkin O. O. Soloshenkova L. I. Novikova N. P. Rechnova |
| author_sort | I. I. Chukaeva |
| collection | DOAJ |
| description | In patients with myocardial infarction, the dynamics of acute phase proteins (APP), oxidative stress and white blood cell functional activity was investigated. A statistically significant increase in APP levels was observed starting from Day 1, reached its peak at Day 7, and disappeared by Day 28. Acute phase parameters correlated with oxidative stress characteristics. APP levels were higher in patients with more severe clinical course. The rate of haptoglobin concentration reduction was higher in participants receiving ACE inhibitors, comparing to the control group. Therefore, ACE inhibitor therapy might affect inflammation and sclerosis processes in the infarction area. |
| first_indexed | 2024-04-09T20:52:43Z |
| format | Article |
| id | doaj.art-f7a80b708a9443c7ba0b5318e369aab8 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:52:43Z |
| publishDate | 2009-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-f7a80b708a9443c7ba0b5318e369aab82023-03-29T21:23:16Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202009-10-010530341172INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGYI. I. Chukaeva0N. V. Orlova1F. A. Evdokimov2V. A. Aleshkin3O. O. Soloshenkova4L. I. Novikova5N. P. Rechnova6ГОУ ВПО РГМУ Росздрава, кафедра поликлинической терапии, МоскваГОУ ВПО РГМУ Росздрава, кафедра поликлинической терапии, МоскваГОУ ВПО РГМУ Росздрава, кафедра поликлинической терапии, МоскваМосковский научно исследовательский институт эпидемиологии и микробиологии им. Н.Г.Габричевского, МоскваГОУ ВПО РГМУ Росздрава, кафедра поликлинической терапии, МоскваМосковский научно исследовательский институт эпидемиологии и микробиологии им. Н.Г.Габричевского, Москва13 ГКБ, МоскваIn patients with myocardial infarction, the dynamics of acute phase proteins (APP), oxidative stress and white blood cell functional activity was investigated. A statistically significant increase in APP levels was observed starting from Day 1, reached its peak at Day 7, and disappeared by Day 28. Acute phase parameters correlated with oxidative stress characteristics. APP levels were higher in patients with more severe clinical course. The rate of haptoglobin concentration reduction was higher in participants receiving ACE inhibitors, comparing to the control group. Therefore, ACE inhibitor therapy might affect inflammation and sclerosis processes in the infarction area.https://russjcardiol.elpub.ru/jour/article/view/1383myocardial infarction prognosisinflammationacute phase proteinsoxidative stressace inhibitors |
| spellingShingle | I. I. Chukaeva N. V. Orlova F. A. Evdokimov V. A. Aleshkin O. O. Soloshenkova L. I. Novikova N. P. Rechnova INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY Российский кардиологический журнал myocardial infarction prognosis inflammation acute phase proteins oxidative stress ace inhibitors |
| title | INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY |
| title_full | INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY |
| title_fullStr | INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY |
| title_full_unstemmed | INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY |
| title_short | INFLAMMATION ROLE AND ANTI-INFLAMMATORY STRATEGIES IN ACUTE CARDIOVASCULAR PATHOLOGY |
| title_sort | inflammation role and anti inflammatory strategies in acute cardiovascular pathology |
| topic | myocardial infarction prognosis inflammation acute phase proteins oxidative stress ace inhibitors |
| url | https://russjcardiol.elpub.ru/jour/article/view/1383 |
| work_keys_str_mv | AT iichukaeva inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT nvorlova inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT faevdokimov inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT vaaleshkin inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT oosoloshenkova inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT linovikova inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology AT nprechnova inflammationroleandantiinflammatorystrategiesinacutecardiovascularpathology |