Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice

Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice

ObjectiveCodonopsis Radix and Polygonati Rhizoma (CRPR) has a good hypoglycemic effect. The aims of the present study were to investigate the effect of CRPR on high-fat/high-sugar diet (HFHSD)- and streptozotocin (STZ)-induced type 2 diabetes mellitus (T2DM) mice as well as to investigate the involv...

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Bibliographic Details
Main Authors: Yong-po Mao, Yi-ming Song, Sheng-wang Pan, Ning Li, Wen-xiang Wang, Bin-bin Feng, Jian-hai Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
type 2 diabetes mellitus
pathology section
western blotting
hypoglycemic
Codonopsis Radix and Polygonati Rhizoma
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1068555/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1068555/full

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