Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots

Bioelectric impedance spectroscopy (BIS) has been widely used to study the electrical properties of biological tissue based on the characteristics of the complex electrical impedance dispersions. One of the problems in using the BIS method is the length of time required for the data acquisition proc...

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Main Authors: Didik R. Santoso, Bella Pitaloka, Chomsin S. Widodo, Unggul P. Juswono
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/10/3/878
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author Didik R. Santoso
Bella Pitaloka
Chomsin S. Widodo
Unggul P. Juswono
author_facet Didik R. Santoso
Bella Pitaloka
Chomsin S. Widodo
Unggul P. Juswono
author_sort Didik R. Santoso
collection DOAJ
description Bioelectric impedance spectroscopy (BIS) has been widely used to study the electrical properties of biological tissue based on the characteristics of the complex electrical impedance dispersions. One of the problems in using the BIS method is the length of time required for the data acquisition process and possibly data analysis as well. In this research, a compact and work rapidly BIS instrumentation system has been developed at a low cost. It is designed to work in the frequency range of 100 Hz to 100 kHz, which is generally used in the fields of biophysics and medical physics. The BIS instrumentation system is built using several integrated modules. The modules are an AC current source to produce a selectable injection current; a data acquisition system to measure voltage, current, and phase difference rapidly and simultaneously; and software to calculate and display measurement results in the form of Bode and Nyquist plots in real time. The developed BIS system has been validated using a simple RC circuit as the sample being tested. The average time needed in the process of data acquisition and analysis until the formation of impedance dispersion curves in the form of Bode and Nyquist plots, for 54 sample frequencies, is less than one minute. The system is able to identify R and C values of the sample with a maximum error of 1.5%. In addition, some simple application examples are also presented in this paper.
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spelling doaj.art-f7a9b55497a84eee99cea8c132e5747f2022-12-21T18:42:27ZengMDPI AGApplied Sciences2076-34172020-01-0110387810.3390/app10030878app10030878Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist PlotsDidik R. Santoso0Bella Pitaloka1Chomsin S. Widodo2Unggul P. Juswono3Division of Instrumentation, Department of Physics, Brawijaya University, Jl. Veteran Malang 65145, IndonesiaDivision of Instrumentation, Department of Physics, Brawijaya University, Jl. Veteran Malang 65145, IndonesiaDivision of Medical Physics & Biophysics, Department of Physics, Brawijaya University, Jl. Veteran Malang 65145, IndonesiaDivision of Medical Physics & Biophysics, Department of Physics, Brawijaya University, Jl. Veteran Malang 65145, IndonesiaBioelectric impedance spectroscopy (BIS) has been widely used to study the electrical properties of biological tissue based on the characteristics of the complex electrical impedance dispersions. One of the problems in using the BIS method is the length of time required for the data acquisition process and possibly data analysis as well. In this research, a compact and work rapidly BIS instrumentation system has been developed at a low cost. It is designed to work in the frequency range of 100 Hz to 100 kHz, which is generally used in the fields of biophysics and medical physics. The BIS instrumentation system is built using several integrated modules. The modules are an AC current source to produce a selectable injection current; a data acquisition system to measure voltage, current, and phase difference rapidly and simultaneously; and software to calculate and display measurement results in the form of Bode and Nyquist plots in real time. The developed BIS system has been validated using a simple RC circuit as the sample being tested. The average time needed in the process of data acquisition and analysis until the formation of impedance dispersion curves in the form of Bode and Nyquist plots, for 54 sample frequencies, is less than one minute. The system is able to identify R and C values of the sample with a maximum error of 1.5%. In addition, some simple application examples are also presented in this paper.https://www.mdpi.com/2076-3417/10/3/878bis-instrumentationbiological-tissuegain-phase detectorbode plotnyquist plot
spellingShingle Didik R. Santoso
Bella Pitaloka
Chomsin S. Widodo
Unggul P. Juswono
Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
Applied Sciences
bis-instrumentation
biological-tissue
gain-phase detector
bode plot
nyquist plot
title Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
title_full Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
title_fullStr Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
title_full_unstemmed Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
title_short Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots
title_sort low cost compact and rapid bio impedance spectrometer with real time bode and nyquist plots
topic bis-instrumentation
biological-tissue
gain-phase detector
bode plot
nyquist plot
url https://www.mdpi.com/2076-3417/10/3/878
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AT bellapitaloka lowcostcompactandrapidbioimpedancespectrometerwithrealtimebodeandnyquistplots
AT chomsinswidodo lowcostcompactandrapidbioimpedancespectrometerwithrealtimebodeandnyquistplots
AT unggulpjuswono lowcostcompactandrapidbioimpedancespectrometerwithrealtimebodeandnyquistplots