Aberrant methylation of the promoter regions of the SOX7 and p15INK4b genes and Wnt signaling pathway antagonists in patients with acute myeloid leukemias

Aberrant methylation of the promoter regions of the SOX7 and p15INK4b genes and Wnt signaling pathway antagonists in patients with acute myeloid leukemias

Aim. To investigate the methylation status of the SOX7 and p15NK4b genes and Wnt signaling pathway antagonists in patients with acute myeloid leukemia (AML) in order to assess the association of the rate of aberrant methylation (AM) with the morphological variant and pattern of chromosomal aberratio...

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Bibliographic Details
Main Authors: I I Kostroma, S V Gritsaev, Zh Yu Sidorova, S A Tiranova, S P Svitina, Yu S Drizhun, Zh V Chubukina, I S Martynkevich, S I Kapustin, S S Bessmeltsev
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2016-07-01
Series:Терапевтический архив
Subjects:
acute myeloid leukemia
aberrant methylation
sox7
p15nk4b
wnt antagonists
p15ink4b
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/31989/pdf

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