Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method
(1) Background: As increases in intra-abdominal pressure (IAP) result in irreversible tissue damage, monitoring IAP in critically ill patients using the common urinary bladder catheter method is essential. However, this method can result in complications and is not suitable for very low birth weight...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/10/8/1422 |
| _version_ | 1797585150058430464 |
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| author | Deirdre Vincent Stefan Mietzsch Wolfgang Braun Magdalena Trochimiuk Konrad Reinshagen Michael Boettcher |
| author_facet | Deirdre Vincent Stefan Mietzsch Wolfgang Braun Magdalena Trochimiuk Konrad Reinshagen Michael Boettcher |
| author_sort | Deirdre Vincent |
| collection | DOAJ |
| description | (1) Background: As increases in intra-abdominal pressure (IAP) result in irreversible tissue damage, monitoring IAP in critically ill patients using the common urinary bladder catheter method is essential. However, this method can result in complications and is not suitable for very low birth weight neonates. The aim of this study was to establish a non-invasive and accurate method to detect IAP changes using an animal model. (2) Methods: IAP changes via intra-abdominal air application (up to 20 mmHg) were measured in 19 Wistar rats via an intra-abdominally placed intracranial pressure probe. Concurrently, abdominal surface tension was measured using a Graseby capsule (GC). (3) Results: A high correlation between abdominal wall distension and IAP (r = 0.9264, CI 0.9249–0.9279) was found for all subjects. (4) Conclusions: IAP changes in rats can be detected non-invasively using a GC. However, further studies are necessary to assess whether IAP changes can be measured using a GC in the neonatal population. |
| first_indexed | 2024-03-11T00:02:54Z |
| format | Article |
| id | doaj.art-f7adde93c7f74879a08c1ed5b4d208de |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T00:02:54Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-f7adde93c7f74879a08c1ed5b4d208de2023-11-19T00:41:25ZengMDPI AGChildren2227-90672023-08-01108142210.3390/children10081422Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection MethodDeirdre Vincent0Stefan Mietzsch1Wolfgang Braun2Magdalena Trochimiuk3Konrad Reinshagen4Michael Boettcher5Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyFritz Stephan GmbH, 56412 Gackenbach, GermanyDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany(1) Background: As increases in intra-abdominal pressure (IAP) result in irreversible tissue damage, monitoring IAP in critically ill patients using the common urinary bladder catheter method is essential. However, this method can result in complications and is not suitable for very low birth weight neonates. The aim of this study was to establish a non-invasive and accurate method to detect IAP changes using an animal model. (2) Methods: IAP changes via intra-abdominal air application (up to 20 mmHg) were measured in 19 Wistar rats via an intra-abdominally placed intracranial pressure probe. Concurrently, abdominal surface tension was measured using a Graseby capsule (GC). (3) Results: A high correlation between abdominal wall distension and IAP (r = 0.9264, CI 0.9249–0.9279) was found for all subjects. (4) Conclusions: IAP changes in rats can be detected non-invasively using a GC. However, further studies are necessary to assess whether IAP changes can be measured using a GC in the neonatal population.https://www.mdpi.com/2227-9067/10/8/1422acute abdomenanimal modelGraseby capsuleintra-abdominal pressureneonatal intensive care |
| spellingShingle | Deirdre Vincent Stefan Mietzsch Wolfgang Braun Magdalena Trochimiuk Konrad Reinshagen Michael Boettcher Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method Children acute abdomen animal model Graseby capsule intra-abdominal pressure neonatal intensive care |
| title | Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method |
| title_full | Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method |
| title_fullStr | Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method |
| title_full_unstemmed | Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method |
| title_short | Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method |
| title_sort | abdominal wall movements predict intra abdominal pressure changes in rats a novel non invasive intra abdominal pressure detection method |
| topic | acute abdomen animal model Graseby capsule intra-abdominal pressure neonatal intensive care |
| url | https://www.mdpi.com/2227-9067/10/8/1422 |
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