A prebiotic basis for ATP as the universal energy currency.

A prebiotic basis for ATP as the universal energy currency.

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ATP is universally conserved as the principal energy currency in cells, driving metabolism through phosphorylation and condensation reactions. Such deep conservation suggests that ATP arose at an early stage of biochemical evolution. Yet purine synthesis requires 6 phosphorylation steps linked to AT...

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Bibliographic Details
Main Authors: Silvana Pinna, Cäcilia Kunz, Aaron Halpern, Stuart A Harrison, Sean F Jordan, John Ward, Finn Werner, Nick Lane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001437

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