Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials
Intermittent fasting (IF) and caloric restriction (CR) are dietary strategies to prevent and attenuate obesity associated with conditions and aging-related outcomes. This scoping review examined the cardiometabolic, cancer, and neurocognitive outcome differences between IF and CR interventions among...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/2/316 |
| _version_ | 1797339515911667712 |
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| author | Dara L. James Nanako A. Hawley Alex E. Mohr Janice Hermer Edward Ofori Fang Yu Dorothy D. Sears |
| author_facet | Dara L. James Nanako A. Hawley Alex E. Mohr Janice Hermer Edward Ofori Fang Yu Dorothy D. Sears |
| author_sort | Dara L. James |
| collection | DOAJ |
| description | Intermittent fasting (IF) and caloric restriction (CR) are dietary strategies to prevent and attenuate obesity associated with conditions and aging-related outcomes. This scoping review examined the cardiometabolic, cancer, and neurocognitive outcome differences between IF and CR interventions among adults. We applied a systematic approach to scope published randomized controlled trials (databases: PubMed, CINAHL Plus, PsychInfo, Scopus, and Google Scholar) from inception through August 2023. The initial search provided 389 unique articles which were critically appraised. Thirty articles met the eligibility criteria for inclusion: 12 were IF, 10 were CR, and 8 were combined IF and CR interventions. IF and CR were associated with weight loss; however, IF studies tended to report greater adherence compared with CR. Overall, IF and CR were equivalently effective across cardiometabolic, cancer, and neurocognitive outcomes. Our findings suggest that IF has health benefits in a variety of conditions and may be better accepted and tolerated than CR, but more comparative research is required. |
| first_indexed | 2024-03-08T09:49:17Z |
| format | Article |
| id | doaj.art-f7b2a71850d644d18191f6998984caf1 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T09:49:17Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f7b2a71850d644d18191f6998984caf12024-01-29T14:10:26ZengMDPI AGNutrients2072-66432024-01-0116231610.3390/nu16020316Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled TrialsDara L. James0Nanako A. Hawley1Alex E. Mohr2Janice Hermer3Edward Ofori4Fang Yu5Dorothy D. Sears6Edson College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, AZ 85004, USADepartment of Psychology, College of Arts and Sciences, University of South Alabama, Mobile, AL 36688, USACollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USAArizona State University Library, Arizona State University, Phoenix, AZ 85004, USACollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USAEdson College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, AZ 85004, USACollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USAIntermittent fasting (IF) and caloric restriction (CR) are dietary strategies to prevent and attenuate obesity associated with conditions and aging-related outcomes. This scoping review examined the cardiometabolic, cancer, and neurocognitive outcome differences between IF and CR interventions among adults. We applied a systematic approach to scope published randomized controlled trials (databases: PubMed, CINAHL Plus, PsychInfo, Scopus, and Google Scholar) from inception through August 2023. The initial search provided 389 unique articles which were critically appraised. Thirty articles met the eligibility criteria for inclusion: 12 were IF, 10 were CR, and 8 were combined IF and CR interventions. IF and CR were associated with weight loss; however, IF studies tended to report greater adherence compared with CR. Overall, IF and CR were equivalently effective across cardiometabolic, cancer, and neurocognitive outcomes. Our findings suggest that IF has health benefits in a variety of conditions and may be better accepted and tolerated than CR, but more comparative research is required.https://www.mdpi.com/2072-6643/16/2/316dietary fastingenergy restrictioncircadian rhythmtime-restricted eatingnightly fasting |
| spellingShingle | Dara L. James Nanako A. Hawley Alex E. Mohr Janice Hermer Edward Ofori Fang Yu Dorothy D. Sears Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials Nutrients dietary fasting energy restriction circadian rhythm time-restricted eating nightly fasting |
| title | Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials |
| title_full | Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials |
| title_fullStr | Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials |
| title_full_unstemmed | Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials |
| title_short | Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials |
| title_sort | impact of intermittent fasting and or caloric restriction on aging related outcomes in adults a scoping review of randomized controlled trials |
| topic | dietary fasting energy restriction circadian rhythm time-restricted eating nightly fasting |
| url | https://www.mdpi.com/2072-6643/16/2/316 |
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