R-spondin family biology and emerging linkages to cancer

R-spondin family biology and emerging linkages to cancer

AbstractThe R-spondin protein family comprises four members (RSPO1-4), which are agonists of the canonical Wnt/β-catenin pathway. Emerging evidence revealed that RSPOs should not only be viewed as agonists of the Wnt/β-catenin pathway but also as regulators for tumor development and progression. Abe...

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Bibliographic Details
Main Authors:	Zhimin He, Jialin Zhang, Jianzhong Ma, Lei Zhao, Xiaodong Jin, Hongbin Li
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Series:	Annals of Medicine
Subjects:	R-spondin WNT signaling LGR4/5/6 tumor microenvironment targeted therapy biomarker
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2023.2166981

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