GYY4137 Promotes Mice Feeding Behavior via Arcuate Nucleus Sulfur-Sulfhydrylation and AMPK Activation

GYY4137 Promotes Mice Feeding Behavior via Arcuate Nucleus Sulfur-Sulfhydrylation and AMPK Activation

Hydrogen sulfide (H2S) is an endogenous gaseous molecule and plays important biological and neurochemical roles in many processes such as the neural activity and immunity. The arcuate nucleus (ARC) of hypothalamus is a control center for appetite and energy metabolism. AMPK is a gage kinase in the m...

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Bibliographic Details
Main Authors: Jun Zhou, Xiao-Hui Lv, Jun-Juan Fan, Li-Yun Dang, Kun Dong, Bo Gao, Ao-Qi Song, Wen-Ning Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
hydrogen sulfide
arcuate nucleus
GYY4137
food intake
AMPK
sulfur-sulfhydrylation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00966/full

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