Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus)
This study aimed to compare the effect of red dragon fruit extract (Hylocereus polyrhizus) and white dragon fruit extract (Hylocereus undatus) to total cholesterol levels in white rats (Rattus norvegicus). Total of 30 males white wistar strains were divided into five treatments i.e: (1) standard fee...
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| Format: | Article |
| Language: | English |
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Bogor Agricultural University
2018-02-01
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| Series: | Jurnal Gizi dan Pangan |
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| Online Access: | https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/20354 |
| _version_ | 1797672528373612544 |
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| author | Luthfi Octafyan Prakoso Hany Yusmaini Maria Selvester Thadeus Sugeng Wiyono |
| author_facet | Luthfi Octafyan Prakoso Hany Yusmaini Maria Selvester Thadeus Sugeng Wiyono |
| author_sort | Luthfi Octafyan Prakoso |
| collection | DOAJ |
| description | This study aimed to compare the effect of red dragon fruit extract (Hylocereus polyrhizus) and white dragon fruit extract (Hylocereus undatus) to total cholesterol levels in white rats (Rattus norvegicus). Total of 30 males white wistar strains were divided into five treatments i.e: (1) standard feed and Na-CMC 1% (K1), (2) standard feed and quail egg 10ml/kgBW (K2), (3) standard feed, quail egg 10ml/kgBW and simvastatin dose 0,72mg/day (P1), (4) standard feed, quail egg 10ml/kgBW and red dragon fruit extract dose 60mg/200gBW/day (P2), (3) standard feed, quail egg 10 ml/kgBW and white dragon fruit extract dose 120mg/200gBW/day (P3). The intervention was carried out for 14 days after 7 days acclimatization period. Data was analyzed by One Way ANOVA test and continued with Post Hoc Bonferroni test (p=0.05). In P2 group, there was a difference of total blood cholesterol level by 25.83 mg/dl compared with the positive control group and statistically significant (p<0.05). In P1 and P3 group there were difference in cholesterol levels of 9.5 mg/dl and 11.5 mg/dl compared with the positive control group, but not statistically significant (p>0.05). The comparison between red dragon extract group and white dragon extract showed a non-significant difference (p>0.05). Red dragon fruit extract and white dragon extract have a potential effect to improve hypercholesterolemia conditions. |
| first_indexed | 2024-03-11T21:32:20Z |
| format | Article |
| id | doaj.art-f7b632aa7f8b4adabdba7d4f051701e5 |
| institution | Directory Open Access Journal |
| issn | 1978-1059 2407-0920 |
| language | English |
| last_indexed | 2024-03-11T21:32:20Z |
| publishDate | 2018-02-01 |
| publisher | Bogor Agricultural University |
| record_format | Article |
| series | Jurnal Gizi dan Pangan |
| spelling | doaj.art-f7b632aa7f8b4adabdba7d4f051701e52023-09-27T08:48:07ZengBogor Agricultural UniversityJurnal Gizi dan Pangan1978-10592407-09202018-02-0112310.25182/jgp.2017.12.3.195-20220354Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus)Luthfi Octafyan Prakoso0Hany Yusmaini1Maria Selvester Thadeus2Sugeng Wiyono3Progam Studi Sarjana Kedokteran, UPN “Veteran” Jakarta, Jakarta 12450Departemen Farmakologi, Fakultas Kedokteran, UPN “Veteran” Jakarta, Jakarta 12450Departemen Patologi Anatomi, Fakultas Kedokteran UPN “Veteran” Jakarta, Jakarta 12450Jurusan Gizi, Poltekkes Kemenkes Jakarta II, Jakarta 12120This study aimed to compare the effect of red dragon fruit extract (Hylocereus polyrhizus) and white dragon fruit extract (Hylocereus undatus) to total cholesterol levels in white rats (Rattus norvegicus). Total of 30 males white wistar strains were divided into five treatments i.e: (1) standard feed and Na-CMC 1% (K1), (2) standard feed and quail egg 10ml/kgBW (K2), (3) standard feed, quail egg 10ml/kgBW and simvastatin dose 0,72mg/day (P1), (4) standard feed, quail egg 10ml/kgBW and red dragon fruit extract dose 60mg/200gBW/day (P2), (3) standard feed, quail egg 10 ml/kgBW and white dragon fruit extract dose 120mg/200gBW/day (P3). The intervention was carried out for 14 days after 7 days acclimatization period. Data was analyzed by One Way ANOVA test and continued with Post Hoc Bonferroni test (p=0.05). In P2 group, there was a difference of total blood cholesterol level by 25.83 mg/dl compared with the positive control group and statistically significant (p<0.05). In P1 and P3 group there were difference in cholesterol levels of 9.5 mg/dl and 11.5 mg/dl compared with the positive control group, but not statistically significant (p>0.05). The comparison between red dragon extract group and white dragon extract showed a non-significant difference (p>0.05). Red dragon fruit extract and white dragon extract have a potential effect to improve hypercholesterolemia conditions.https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/20354Rattus norvegicusred dragon fruit extracttotal cholesterolwhite dragon fruit extract |
| spellingShingle | Luthfi Octafyan Prakoso Hany Yusmaini Maria Selvester Thadeus Sugeng Wiyono Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) Jurnal Gizi dan Pangan Rattus norvegicus red dragon fruit extract total cholesterol white dragon fruit extract |
| title | Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) |
| title_full | Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) |
| title_fullStr | Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) |
| title_full_unstemmed | Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) |
| title_short | Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) |
| title_sort | perbedaan efek ekstrak buah naga merah hylocereus polyrhizus dan ekstrak buah naga putih hylocereus undatus terhadap kadar kolesterol total tikus putih rattus norvegicus |
| topic | Rattus norvegicus red dragon fruit extract total cholesterol white dragon fruit extract |
| url | https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/20354 |
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