Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides

Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides

Three series of 6-aryl-2-methylnicotinohydrazides 4a–i, N′-arylidene-6-(4-bromophenyl)-2-methylnicotino hydrazides 7a–f, and N′-(un/substituted 2-oxoindolin-3-ylidene)-6-(4-fluorophenyl)-2-methylnicotinohydrazides 8a–c were synthesized and evaluated for their potential in vitro antimycobacterial act...

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Bibliographic Details
Main Authors: Wagdy M. Eldehna, Mohamed Fares, Marwa M. Abdel-Aziz, Hatem A. Abdel-Aziz
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
synthesis
nicotinic acid
hydrazides
antimycobacterial
ADME
Online Access:http://www.mdpi.com/1420-3049/20/5/8800

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