In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis
<p>Abstract</p> <p>Background</p> <p>A common sequence polymorphism at codon 72 of the p53 gene encoding either arginine or proline was recently shown to be functionally relevant for apoptosis induction in vitro. In B-type chronic lymphocytic leukemia (B-CLL), p53 gene...
Main Authors: | Dörken Bernd, Bosanquet Andrew G, Hummel Michael, Sturm Isrid, Daniel Peter T |
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Format: | Article |
Language: | English |
Published: |
BMC
2005-08-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/5/105 |
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