Intravenous administration of human Muse cells recovers blood flow in a mouse model of hindlimb ischemia

Intravenous administration of human Muse cells recovers blood flow in a mouse model of hindlimb ischemia

Cell-based therapies hold great promise for the treatment of peripheral arterial disease (PAD), especially in patients presenting with severe limb ischemia, although the optimal strategy remains to be explored. In this study, we evaluated the therapeutic effect of intravenous administration of human...

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Bibliographic Details
Main Authors: Yusuke Hori, Tomoya Kitani, Kenji Yanishi, Takaomi Suga, Masaya Kogure, Tetsuro Kusaba, Yoshihiro Kushida, Mari Dezawa, Satoaki Matoba
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
peripheral arterial disease
hindlimb ischemia
cell therapy
Muse cell
mesenchymal stem cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.981088/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.981088/full

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