Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate
Transurethral resection of the prostate (TURP) is the most common standard surgical procedure used for benign prostatic hyperplasia. Transurethral resection in saline (TURis) is a bipolar electrosurgery system used to prevent TURP (or TUR) syndrome. The bicarbonate Ringer's solution is not gene...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Elsevier
2021-03-01
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| মালা: | Contemporary Clinical Trials Communications |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://www.sciencedirect.com/science/article/pii/S2451865421000466 |
| _version_ | 1831547745014382592 |
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| author | Fumiya Hongo Tsukasa Narukawa Atsuko Fujihara Fumimasa Amaya Teiji Sawa Osamu Ukimura |
| author_facet | Fumiya Hongo Tsukasa Narukawa Atsuko Fujihara Fumimasa Amaya Teiji Sawa Osamu Ukimura |
| author_sort | Fumiya Hongo |
| collection | DOAJ |
| description | Transurethral resection of the prostate (TURP) is the most common standard surgical procedure used for benign prostatic hyperplasia. Transurethral resection in saline (TURis) is a bipolar electrosurgery system used to prevent TURP (or TUR) syndrome. The bicarbonate Ringer's solution is not generally used as perfusate for TURP. Hence, we compared the efficacy of the bicarbonate Ringer's solution with that of physiological saline as perfusate during TURP. This prospective, multicenter, cooperative study was conducted on 40 adult patients admitted to a medical college hospital. After obtaining informed consent from all the patients, they were divided into two groups (20 patients per group). For patients of one group, bicarbonate Ringer's solution, and for other group, physiological saline was used as perfusate. Compared to the physiological saline, the electrolyte composition of the bicarbonate Ringer's solution was closer to that of plasma. Hence, the group using bicarbonate Ringer's solution as perfusate was exhibited less variation in plasma electrolytes and blood gas data. The primary endpoints were adverse events of grade 1 or higher according to the JCOG postoperative complication criteria ver. 2.0, unintended diseases, or related signs in patients who underwent the protocol therapy. The secondary endpoints were changes in blood pH, bicarbonate ion level, anion gap (AG), base excess (BE), and chloride (C1), which occurred during and after the surgeries. Therefore, bicarbonate Ringer's solution has superior with that of physiological saline as perfusate during TURP which is directly administered into the blood vessels as an infusion solution.Bicarbonate Ringer's solution is directly administered into the blood vessels as an infusion solution. |
| first_indexed | 2024-12-17T02:08:11Z |
| format | Article |
| id | doaj.art-f7c35b845a1b4d11a6eb0cfa9610fba1 |
| institution | Directory Open Access Journal |
| issn | 2451-8654 |
| language | English |
| last_indexed | 2024-12-17T02:08:11Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Contemporary Clinical Trials Communications |
| spelling | doaj.art-f7c35b845a1b4d11a6eb0cfa9610fba12022-12-21T22:07:39ZengElsevierContemporary Clinical Trials Communications2451-86542021-03-0121100744Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostateFumiya Hongo0Tsukasa Narukawa1Atsuko Fujihara2Fumimasa Amaya3Teiji Sawa4Osamu Ukimura5Department of Urology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, Japan; Corresponding author.Department of Urology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, JapanDepartment of Urology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, JapanDepartment of Pain Management and Palliative Care Medicine, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, JapanDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, JapanDepartment of Urology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi-Hirokoji Kamigyo-ku, Kyoto, 602-8566, JapanTransurethral resection of the prostate (TURP) is the most common standard surgical procedure used for benign prostatic hyperplasia. Transurethral resection in saline (TURis) is a bipolar electrosurgery system used to prevent TURP (or TUR) syndrome. The bicarbonate Ringer's solution is not generally used as perfusate for TURP. Hence, we compared the efficacy of the bicarbonate Ringer's solution with that of physiological saline as perfusate during TURP. This prospective, multicenter, cooperative study was conducted on 40 adult patients admitted to a medical college hospital. After obtaining informed consent from all the patients, they were divided into two groups (20 patients per group). For patients of one group, bicarbonate Ringer's solution, and for other group, physiological saline was used as perfusate. Compared to the physiological saline, the electrolyte composition of the bicarbonate Ringer's solution was closer to that of plasma. Hence, the group using bicarbonate Ringer's solution as perfusate was exhibited less variation in plasma electrolytes and blood gas data. The primary endpoints were adverse events of grade 1 or higher according to the JCOG postoperative complication criteria ver. 2.0, unintended diseases, or related signs in patients who underwent the protocol therapy. The secondary endpoints were changes in blood pH, bicarbonate ion level, anion gap (AG), base excess (BE), and chloride (C1), which occurred during and after the surgeries. Therefore, bicarbonate Ringer's solution has superior with that of physiological saline as perfusate during TURP which is directly administered into the blood vessels as an infusion solution.Bicarbonate Ringer's solution is directly administered into the blood vessels as an infusion solution.http://www.sciencedirect.com/science/article/pii/S2451865421000466Bicarbonate Ringer's solutionTransurethral resection of the prostateTUR syndromePhysiological saline |
| spellingShingle | Fumiya Hongo Tsukasa Narukawa Atsuko Fujihara Fumimasa Amaya Teiji Sawa Osamu Ukimura Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate Contemporary Clinical Trials Communications Bicarbonate Ringer's solution Transurethral resection of the prostate TUR syndrome Physiological saline |
| title | Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate |
| title_full | Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate |
| title_fullStr | Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate |
| title_full_unstemmed | Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate |
| title_short | Usefulness of bicarbonate Ringer's solution as perfusate during transurethral resection of the prostate |
| title_sort | usefulness of bicarbonate ringer s solution as perfusate during transurethral resection of the prostate |
| topic | Bicarbonate Ringer's solution Transurethral resection of the prostate TUR syndrome Physiological saline |
| url | http://www.sciencedirect.com/science/article/pii/S2451865421000466 |
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