Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro

Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro

Somatostatin is an inhibitory peptide, which regulates the release of several hormones, and affects neurotransmission and cell proliferation via its five G<sub>i</sub> protein-coupled receptors (SST<sub>1-5</sub>). Although its endocrine regulatory and anti-tumour effects hav...

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Bibliographic Details
Main Authors: Muhammad Aslam, Hafiza Idrees, Peter Ferdinandy, Zsuzsanna Helyes, Christian Hamm, Rainer Schulz
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
somatostatin receptors
Akt
MAPK
angiogenesis
endothelial permeability
RhoA/Rock
Online Access:https://www.mdpi.com/1422-0067/23/6/3098

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