The Role of the FODMAP Diet in IBS
The low FODMAP (fermentable oligosaccharide, disaccharide, monosaccharide, and polyol) diet is a beneficial therapeutic approach for patients with irritable bowel syndrome (IBS). However, how the low FODMAP diet works is still not completely understood. These mechanisms encompass not only traditiona...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/3/370 |
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| author | Luisa Bertin Miriana Zanconato Martina Crepaldi Giovanni Marasco Cesare Cremon Giovanni Barbara Brigida Barberio Fabiana Zingone Edoardo Vincenzo Savarino |
| author_facet | Luisa Bertin Miriana Zanconato Martina Crepaldi Giovanni Marasco Cesare Cremon Giovanni Barbara Brigida Barberio Fabiana Zingone Edoardo Vincenzo Savarino |
| author_sort | Luisa Bertin |
| collection | DOAJ |
| description | The low FODMAP (fermentable oligosaccharide, disaccharide, monosaccharide, and polyol) diet is a beneficial therapeutic approach for patients with irritable bowel syndrome (IBS). However, how the low FODMAP diet works is still not completely understood. These mechanisms encompass not only traditionally known factors such as luminal distension induced by gas and water but also recent evidence on the role of FOMAPs in the modulation of visceral hypersensitivity, increases in intestinal permeability, the induction of microbiota changes, and the production of short-chain fatty acids (SCFAs), as well as metabolomics and alterations in motility. Although most of the supporting evidence is of low quality, recent trials have confirmed its effectiveness, even though the majority of the evidence pertains only to the restriction phase and its effectiveness in relieving abdominal bloating and pain. This review examines potential pathophysiological mechanisms and provides an overview of the existing evidence on the effectiveness of the low FODMAP diet across various IBS subtypes. Key considerations for its use include the challenges and disadvantages associated with its practical implementation, including the need for professional guidance, variations in individual responses, concerns related to microbiota, nutritional deficiencies, the development of constipation, the necessity of excluding an eating disorder before commencing the diet, and the scarcity of long-term data. Despite its recognized efficacy in symptom management, acknowledging these limitations becomes imperative for a nuanced comprehension of the role of a low FODMAP diet in managing IBS. By investigating its potential mechanisms and evidence across IBS subtypes and addressing emerging modulations alongside limitations, this review aims to serve as a valuable resource for healthcare practitioners, researchers, and patients navigating the intricate landscape of IBS. |
| first_indexed | 2024-03-08T03:52:17Z |
| format | Article |
| id | doaj.art-f7c91c43ca1e4da2a8db63292af72b57 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T03:52:17Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f7c91c43ca1e4da2a8db63292af72b572024-02-09T15:19:44ZengMDPI AGNutrients2072-66432024-01-0116337010.3390/nu16030370The Role of the FODMAP Diet in IBSLuisa Bertin0Miriana Zanconato1Martina Crepaldi2Giovanni Marasco3Cesare Cremon4Giovanni Barbara5Brigida Barberio6Fabiana Zingone7Edoardo Vincenzo Savarino8Department of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyIRCCS Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, ItalyIRCCS Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, ItalyIRCCS Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, ItalyDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35121 Padua, ItalyThe low FODMAP (fermentable oligosaccharide, disaccharide, monosaccharide, and polyol) diet is a beneficial therapeutic approach for patients with irritable bowel syndrome (IBS). However, how the low FODMAP diet works is still not completely understood. These mechanisms encompass not only traditionally known factors such as luminal distension induced by gas and water but also recent evidence on the role of FOMAPs in the modulation of visceral hypersensitivity, increases in intestinal permeability, the induction of microbiota changes, and the production of short-chain fatty acids (SCFAs), as well as metabolomics and alterations in motility. Although most of the supporting evidence is of low quality, recent trials have confirmed its effectiveness, even though the majority of the evidence pertains only to the restriction phase and its effectiveness in relieving abdominal bloating and pain. This review examines potential pathophysiological mechanisms and provides an overview of the existing evidence on the effectiveness of the low FODMAP diet across various IBS subtypes. Key considerations for its use include the challenges and disadvantages associated with its practical implementation, including the need for professional guidance, variations in individual responses, concerns related to microbiota, nutritional deficiencies, the development of constipation, the necessity of excluding an eating disorder before commencing the diet, and the scarcity of long-term data. Despite its recognized efficacy in symptom management, acknowledging these limitations becomes imperative for a nuanced comprehension of the role of a low FODMAP diet in managing IBS. By investigating its potential mechanisms and evidence across IBS subtypes and addressing emerging modulations alongside limitations, this review aims to serve as a valuable resource for healthcare practitioners, researchers, and patients navigating the intricate landscape of IBS.https://www.mdpi.com/2072-6643/16/3/370FODMAPsnutritional statusfructoselactosefructansgalactans |
| spellingShingle | Luisa Bertin Miriana Zanconato Martina Crepaldi Giovanni Marasco Cesare Cremon Giovanni Barbara Brigida Barberio Fabiana Zingone Edoardo Vincenzo Savarino The Role of the FODMAP Diet in IBS Nutrients FODMAPs nutritional status fructose lactose fructans galactans |
| title | The Role of the FODMAP Diet in IBS |
| title_full | The Role of the FODMAP Diet in IBS |
| title_fullStr | The Role of the FODMAP Diet in IBS |
| title_full_unstemmed | The Role of the FODMAP Diet in IBS |
| title_short | The Role of the FODMAP Diet in IBS |
| title_sort | role of the fodmap diet in ibs |
| topic | FODMAPs nutritional status fructose lactose fructans galactans |
| url | https://www.mdpi.com/2072-6643/16/3/370 |
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