Proinflammatory mucosal-associated invariant CD8+ T cells react to gut flora yeasts and infiltrate multiple sclerosis brain

Proinflammatory mucosal-associated invariant CD8+ T cells react to gut flora yeasts and infiltrate multiple sclerosis brain

The composition of the intestinal microbiota plays a critical role in shaping the immune system. Modern lifestyle, the inappropriate use of antibiotics, and exposure to pollution have significantly affected the composition of commensal microorganisms. The intestinal microbiota has been shown to sust...

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Bibliographic Details
Main Authors: Francesca Gargano, Gisella Guerrera, Eleonora Piras, Barbara Serafini, Monica Di Paola, Lisa Rizzetto, Maria Chiara Buscarinu, Viviana Annibali, Claudia Vuotto, Marco De Bardi, Silvia D’Orso, Serena Ruggieri, Claudio Gasperini, Lorenzo Pavarini, Giovanni Ristori, Mario Picozza, Barbara Rosicarelli, Clara Ballerini, Rosella Mechelli, Francesco Vitali, Duccio Cavalieri, Marco Salvetti, Daniela F. Angelini, Giovanna Borsellino, Carlotta De Filippo, Luca Battistini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
dysbiosis
mycobiome
MAIT cells
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.890298/full

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