The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic
BACKGROUND AND OBJECTIVE: Abdominal colic during infancy is a common complaint of parents within the first three months after the child’s birth. As the intestinal microflora in these infants is different from non-colic newborns, we aimed to determine the effects of probiotics on t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2015-05-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/browse.php?a_code=A-10-1353-1&slc_lang=en&sid=1 |
| _version_ | 1811295744353632256 |
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| author | Z Akbarian-rad M Haghshenas mojaveri Y Zahedpasha M Ahmadpour-kacho K Hajian tileki Y Taghipour |
| author_facet | Z Akbarian-rad M Haghshenas mojaveri Y Zahedpasha M Ahmadpour-kacho K Hajian tileki Y Taghipour |
| author_sort | Z Akbarian-rad |
| collection | DOAJ |
| description | BACKGROUND AND OBJECTIVE: Abdominal colic during infancy is a common complaint of parents within the first three months after the child’s birth. As the intestinal microflora in these infants is different from non-colic newborns, we aimed to determine the effects of probiotics on the balance of intestinal microflora and reducing restlessness in infants with colic.
METHODS: This randomized clinical trial was performed on 44 breastfed infants (20-60 days old), with a birth weight of > 2500 g, suffering from colic, based on Wessel’s definition. These infants received 1-5 drops of placebo (label 1) per day for five consecutive days. Afterwards, they were administered 2-5 drops of Lactobacillus reuteri (label2) (17938 DSM) per day for 14 consecutive days. The parents were contacted twice on a daily basis and the duration of cramps and restlessness in infants was recorded and evaluated (IRCT=2014012713489).
FINDINGS: Among 44 infants, 36 cases completed the study. The mean period of restlessness after 5 days of receiving placebo and L. reuteri was 275±142.8 and 172±88.3 min, respectively (p<0.001). Also, after 14 days of L. reuteri administration, the mean period of restlessness was 106±53.67 min.
CONCLUSION: The results showed that probiotic L. reuteri reduced crying and restlessness duration in infants
with colic. |
| first_indexed | 2024-04-13T05:37:13Z |
| format | Article |
| id | doaj.art-f7ccc43647954659bd2379ebabb1f70c |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-04-13T05:37:13Z |
| publishDate | 2015-05-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-f7ccc43647954659bd2379ebabb1f70c2022-12-22T03:00:14ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702015-05-01175711The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with ColicZ Akbarian-rad0M Haghshenas mojaveri1Y Zahedpasha2M Ahmadpour-kacho3K Hajian tileki4Y Taghipour5 BACKGROUND AND OBJECTIVE: Abdominal colic during infancy is a common complaint of parents within the first three months after the child’s birth. As the intestinal microflora in these infants is different from non-colic newborns, we aimed to determine the effects of probiotics on the balance of intestinal microflora and reducing restlessness in infants with colic. METHODS: This randomized clinical trial was performed on 44 breastfed infants (20-60 days old), with a birth weight of > 2500 g, suffering from colic, based on Wessel’s definition. These infants received 1-5 drops of placebo (label 1) per day for five consecutive days. Afterwards, they were administered 2-5 drops of Lactobacillus reuteri (label2) (17938 DSM) per day for 14 consecutive days. The parents were contacted twice on a daily basis and the duration of cramps and restlessness in infants was recorded and evaluated (IRCT=2014012713489). FINDINGS: Among 44 infants, 36 cases completed the study. The mean period of restlessness after 5 days of receiving placebo and L. reuteri was 275±142.8 and 172±88.3 min, respectively (p<0.001). Also, after 14 days of L. reuteri administration, the mean period of restlessness was 106±53.67 min. CONCLUSION: The results showed that probiotic L. reuteri reduced crying and restlessness duration in infants with colic.http://jbums.org/browse.php?a_code=A-10-1353-1&slc_lang=en&sid=1Lactobacillus Lactobacillus Reuteri Colic Infant Colic Probiotic |
| spellingShingle | Z Akbarian-rad M Haghshenas mojaveri Y Zahedpasha M Ahmadpour-kacho K Hajian tileki Y Taghipour The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul Lactobacillus Lactobacillus Reuteri Colic Infant Colic Probiotic |
| title | The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic |
| title_full | The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic |
| title_fullStr | The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic |
| title_full_unstemmed | The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic |
| title_short | The Effect of Probiotic Lactobacillus Reuteri on Reducing the Period of Restlessness in Infants with Colic |
| title_sort | effect of probiotic lactobacillus reuteri on reducing the period of restlessness in infants with colic |
| topic | Lactobacillus Lactobacillus Reuteri Colic Infant Colic Probiotic |
| url | http://jbums.org/browse.php?a_code=A-10-1353-1&slc_lang=en&sid=1 |
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