Parasite and Cancer Relationship

Cancer is a life-threatening disease that occurs as a result of the uncontrolled proliferation of cells in any organ or tissue of the body. Parasites are dangerous organisms that can cause death in some cases. Parasite and cancer cells are similar in their capacity to survive and proliferate indepen...

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Main Authors: Figen Çelik, Sami Şimşek
Format: Article
Language:English
Published: Galenos Yayinevi 2022-06-01
Series:Türkiye Parazitoloji Dergisi
Subjects:
Online Access: http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/parasite-and-cancer-relationship/51977
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author Figen Çelik
Sami Şimşek
author_facet Figen Çelik
Sami Şimşek
author_sort Figen Çelik
collection DOAJ
description Cancer is a life-threatening disease that occurs as a result of the uncontrolled proliferation of cells in any organ or tissue of the body. Parasites are dangerous organisms that can cause death in some cases. Parasite and cancer cells are similar in their capacity to survive and proliferate independently of exogenous growth factors, to be resistant to apoptosis, and to evade host immune mechanisms. Therefore, it is difficult for the body to completely get rid of cancer cells and parasitic agents. In vitro studies or experimental animal studies examining the parasite-cancer relationship have shown that besides parasites that can cause cancer directly, there are also parasites that can indirectly stimulate cancer development through various mechanisms. On the other hand, it is known that the immune response against some parasites can show antitumoral activity in the body. Parasitic agents can have both tumoral and antitumoral effects through regulation of immune response, prevention of metastasis and angiogenesis, inhibition of proliferative signals, and regulation of inflammatory responses that induce cancer development.
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spelling doaj.art-f7d09e8eaf7f4162b14fa0f7d80108f52023-02-15T16:14:14ZengGalenos YayineviTürkiye Parazitoloji Dergisi1300-63202146-30772022-06-0146215016210.4274/tpd.galenos.2022.3097413049054Parasite and Cancer RelationshipFigen Çelik0Sami Şimşek1 Fırat Üniversitesi Veteriner Fakültesi, Parazitoloji Anabilim Dalı, Elazığ, Türkiye Fırat Üniversitesi Veteriner Fakültesi, Parazitoloji Anabilim Dalı, Elazığ, Türkiye Cancer is a life-threatening disease that occurs as a result of the uncontrolled proliferation of cells in any organ or tissue of the body. Parasites are dangerous organisms that can cause death in some cases. Parasite and cancer cells are similar in their capacity to survive and proliferate independently of exogenous growth factors, to be resistant to apoptosis, and to evade host immune mechanisms. Therefore, it is difficult for the body to completely get rid of cancer cells and parasitic agents. In vitro studies or experimental animal studies examining the parasite-cancer relationship have shown that besides parasites that can cause cancer directly, there are also parasites that can indirectly stimulate cancer development through various mechanisms. On the other hand, it is known that the immune response against some parasites can show antitumoral activity in the body. Parasitic agents can have both tumoral and antitumoral effects through regulation of immune response, prevention of metastasis and angiogenesis, inhibition of proliferative signals, and regulation of inflammatory responses that induce cancer development. http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/parasite-and-cancer-relationship/51977 cancerparasitedrugantigen
spellingShingle Figen Çelik
Sami Şimşek
Parasite and Cancer Relationship
Türkiye Parazitoloji Dergisi
cancer
parasite
drug
antigen
title Parasite and Cancer Relationship
title_full Parasite and Cancer Relationship
title_fullStr Parasite and Cancer Relationship
title_full_unstemmed Parasite and Cancer Relationship
title_short Parasite and Cancer Relationship
title_sort parasite and cancer relationship
topic cancer
parasite
drug
antigen
url http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/parasite-and-cancer-relationship/51977
work_keys_str_mv AT figencelik parasiteandcancerrelationship
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