QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes?
Purpose: Strokes results in a multitude of electrocardiographic (ECG) changes, and a prolongation of the QTc interval is a well-observed one. We analyzed QTc interval prolongation among males and females who presented with acute stroke. Material and Methods: This observational study was conducted a...
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| Format: | Article |
| Language: | English |
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Cukurova University
2014-02-01
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| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=40984 |
| _version_ | 1797906133915009024 |
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| author | Osama Shukir Muhammed Amin Hawar Adnan Myckan Emad Hama Hussein |
| author_facet | Osama Shukir Muhammed Amin Hawar Adnan Myckan Emad Hama Hussein |
| author_sort | Osama Shukir Muhammed Amin |
| collection | DOAJ |
| description | Purpose: Strokes results in a multitude of electrocardiographic (ECG) changes, and a prolongation of the QTc interval is a well-observed one. We analyzed QTc interval prolongation among males and females who presented with acute stroke.
Material and Methods: This observational study was conducted at the department of neurology of the Sulaimaniya general teaching hospital, from August 2012 to May 2013, and involved 100 consecutive patients who presented with acute stroke; 50 had ischemic stroke and the rest (n=50) had hypertensive intracerebral hemorrhage. All patients underwent resting 12-lead ECG within half an hour of A&E admission. The QTc interval was calculated and analyzed. A comparison among males and females in both stroke types was done.
Results: The ischemic group had 25 males and 25 females; 25 patients (25%; 13 males and 12 females) demonstrated QTc interval prolongation. Thirty two males and 18 females constituted the hemorrhagic group; QTc interval prolongation was observed in 18 males and 8 females (n=26; 26%). There was no statistically significant difference in the QTc interval prolongation among males of the ischemic stroke versus hemorrhagic group (P-value<0.73), females of the ischemic versus hemorrhagic group (P-value<0.32), and males and females within the ischemic stroke (P-value<0.40). However, a significant difference was noted between males and females within the hemorrhagic group (P-value<0.09; 95% CI, 481.85 to 530.82).
Conclusion: Only males and females with hypertensive intracerebral hemorrhage demonstrated a statistically significant difference in QTc prolongation in favor of females. Whether this observation is clinically significant or not, it needs further analytic studies. |
| first_indexed | 2024-04-10T10:16:15Z |
| format | Article |
| id | doaj.art-f7d21ddf98d143a09bffc75f6f45835a |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T10:16:15Z |
| publishDate | 2014-02-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-f7d21ddf98d143a09bffc75f6f45835a2023-02-15T16:21:52ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502014-02-01391758240984QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes?Osama Shukir Muhammed Amin0Hawar Adnan Myckan1Emad Hama Hussein2Department of Neurology, Sulaimaniya General Teaching Hospital, Sulaimaniya, Iraq Department of Neurology, Sulaimaniya General Teaching Hospital, Sulaimaniya, Iraq Department of Neurology, Sulaimaniya General Teaching Hospital, Sulaimaniya, IraqPurpose: Strokes results in a multitude of electrocardiographic (ECG) changes, and a prolongation of the QTc interval is a well-observed one. We analyzed QTc interval prolongation among males and females who presented with acute stroke. Material and Methods: This observational study was conducted at the department of neurology of the Sulaimaniya general teaching hospital, from August 2012 to May 2013, and involved 100 consecutive patients who presented with acute stroke; 50 had ischemic stroke and the rest (n=50) had hypertensive intracerebral hemorrhage. All patients underwent resting 12-lead ECG within half an hour of A&E admission. The QTc interval was calculated and analyzed. A comparison among males and females in both stroke types was done. Results: The ischemic group had 25 males and 25 females; 25 patients (25%; 13 males and 12 females) demonstrated QTc interval prolongation. Thirty two males and 18 females constituted the hemorrhagic group; QTc interval prolongation was observed in 18 males and 8 females (n=26; 26%). There was no statistically significant difference in the QTc interval prolongation among males of the ischemic stroke versus hemorrhagic group (P-value<0.73), females of the ischemic versus hemorrhagic group (P-value<0.32), and males and females within the ischemic stroke (P-value<0.40). However, a significant difference was noted between males and females within the hemorrhagic group (P-value<0.09; 95% CI, 481.85 to 530.82). Conclusion: Only males and females with hypertensive intracerebral hemorrhage demonstrated a statistically significant difference in QTc prolongation in favor of females. Whether this observation is clinically significant or not, it needs further analytic studies.http://www.scopemed.org/fulltextpdf.php?mno=40984stroke; QTc interval prolongation; ECG |
| spellingShingle | Osama Shukir Muhammed Amin Hawar Adnan Myckan Emad Hama Hussein QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? Çukurova Üniversitesi Tıp Fakültesi Dergisi stroke; QTc interval prolongation; ECG |
| title | QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? |
| title_full | QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? |
| title_fullStr | QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? |
| title_full_unstemmed | QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? |
| title_short | QTc Interval Prolongation and Stroke: Any Differences between Ischemic and Hemorrhagic Strokes? |
| title_sort | qtc interval prolongation and stroke any differences between ischemic and hemorrhagic strokes |
| topic | stroke; QTc interval prolongation; ECG |
| url | http://www.scopemed.org/fulltextpdf.php?mno=40984 |
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