Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-den...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-10-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3921/7/10/133 |
| _version_ | 1827852844614549504 |
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| author | Sotirios Kiokias Charalampos Proestos Vassilki Oreopoulou |
| author_facet | Sotirios Kiokias Charalampos Proestos Vassilki Oreopoulou |
| author_sort | Sotirios Kiokias |
| collection | DOAJ |
| description | Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes. |
| first_indexed | 2024-03-12T10:57:01Z |
| format | Article |
| id | doaj.art-f7d4f5f47d0649518b247c72b9f481b1 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T10:57:01Z |
| publishDate | 2018-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-f7d4f5f47d0649518b247c72b9f481b12023-09-02T06:19:42ZengMDPI AGAntioxidants2076-39212018-10-0171013310.3390/antiox7100133antiox7100133Effect of Natural Food Antioxidants against LDL and DNA Oxidative ChangesSotirios Kiokias0Charalampos Proestos1Vassilki Oreopoulou2REA-Research Executive Agency, B-1049 Brussels, BelgiumLaboratory of Food Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15784 Athens, GreeceLaboratory of Food Chemistry and Technology, School of Chemical Engineering, National Technical University of Athens, Iron Politechniou 9, 15780 Athens, GreeceRadical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes.http://www.mdpi.com/2076-3921/7/10/133LDL-oxidationDNA-damageantioxidant vitaminsoxidative stress |
| spellingShingle | Sotirios Kiokias Charalampos Proestos Vassilki Oreopoulou Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes Antioxidants LDL-oxidation DNA-damage antioxidant vitamins oxidative stress |
| title | Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes |
| title_full | Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes |
| title_fullStr | Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes |
| title_full_unstemmed | Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes |
| title_short | Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes |
| title_sort | effect of natural food antioxidants against ldl and dna oxidative changes |
| topic | LDL-oxidation DNA-damage antioxidant vitamins oxidative stress |
| url | http://www.mdpi.com/2076-3921/7/10/133 |
| work_keys_str_mv | AT sotirioskiokias effectofnaturalfoodantioxidantsagainstldlanddnaoxidativechanges AT charalamposproestos effectofnaturalfoodantioxidantsagainstldlanddnaoxidativechanges AT vassilkioreopoulou effectofnaturalfoodantioxidantsagainstldlanddnaoxidativechanges |